[1]王 麟,胡 鹏,成景松.两性霉素 B在体外对血清钾测定结果影响的实验观察[J].现代检验医学杂志,2019,34(06):123-125.[doi:10.3969 / j.issn.1671-7414.2019.06.031]
 WANG Lin,HU Peng,CHENG Jing-song.Experimental Observation on the Effect of Amphotericin B on Serum Kalium Determination in Vitro[J].Journal of Modern Laboratory Medicine,2019,34(06):123-125.[doi:10.3969 / j.issn.1671-7414.2019.06.031]
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两性霉素 B在体外对血清钾测定结果影响的实验观察()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第34卷
期数:
2019年06期
页码:
123-125
栏目:
研究简报·实验技术
出版日期:
2019-12-30

文章信息/Info

Title:
Experimental Observation on the Effect of Amphotericin B on Serum Kalium Determination in Vitro
文章编号:
1671-7414(2019)06-123-03
作者:
王 麟1胡 鹏1成景松2
(1. 成都市郫都区中医医院检验科,成都 611730;2. 安康市白河县人民医院检验科,陕西安康 725800)
Author(s):
WANG Lin1 HU Peng1CHENG Jing-song2
(1.Department of Clinical Laboratory, Chengdu Pidu District Hospital of Traditional Chinese Medicine, Chengdu 611730, China; 2.Department of Clinical Laboratory, Baihe County People’s Hospital of Ankang City, Shaanxi Ankang 725800, China)
关键词:
两性霉素B血清钾检验前周转时间
分类号:
R446.112
DOI:
10.3969 / j.issn.1671-7414.2019.06.031
文献标志码:
A
摘要:
目的 研究在应用两性霉素B 药物治疗时检验前周转时间对监测血清钾准确性的影响。方法 对比含有两性 霉素B 药液的实验组和对照组在不同分离时间的血清钾浓度。结果 同对照组相比含两性霉素B 药液的实验组在分离 时间≥ 60min 以上时,血清钾浓度明显增高,并观察到实验组内随时间的延长血清钾浓度也呈明显增高,差异具有统 计学显著性意义(P <0.001)。结论 为保证检验结果的准确性,临床在应用两性霉素B 药物治疗时监测血清钾浓度要 避开血药峰时采血以及采集标本后30 min 内分离血清或血浆立即测定。
Abstract:
Objective To study the effect of pretest turnaround time on the accuracy of serum kalium monitoring in amphotericin B drug therapy. Methods The serum kalium concentrations of amphotericin B solution were compared between the experimental group and the control group at different separation times. Results Compared with the control group, the serum kalium concentration in the experimental group containing amphotericin B solution increased significantly when the separation time was more than 60 min, and it was observed that the serum kalium concentration also increased significantly with the extension of time in the experimental group, with statistically significant difference (F =6.787~21.67,P <0.001). Conclusion In order to ensure the accuracy of the test results, the clinical monitoring of serum kalium concentration during amphotericin B therapy should avoid the blood sampling at the peak of blood drug and the immediate determination of serum or plasma within 30 minutes after sample collection.

参考文献/References:

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备注/Memo

备注/Memo:
作者简介:王麟(1971-),男,副主任技师,研究方向:血液学与生物分子学,E-mail:820922621@qq.com。 通讯作者:成景松(1970-),主任技师,研究方向:生化检验,E-mail:365861611@qq.com。收稿日期:2019-01-31
更新日期/Last Update: 2019-12-25