[1]廖衍强.糖尿病并发高血压患者血清Cys C 与P 物质水平之间的关系研究[J].现代检验医学杂志,2020,35(02):65-67.[doi:10.3969/j.issn.1671-7414.2020.02.019]
　LIAO Yan-qiang.Relationship between Serum Cys C and Substance P Levels in Patientswith Diabetes Mellitus Complicated with Hypertension[J].Journal of Modern Laboratory Medicine,2020,35(02):65-67.[doi:10.3969/j.issn.1671-7414.2020.02.019]
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糖尿病并发高血压患者血清Cys C 与P 物质水平之间的关系研究()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第35卷
期数:
2020年02期
页码:
65-67
栏目:
论　著
出版日期:
2020-05-24

文章信息/Info

Title:
Relationship between Serum Cys C and Substance P Levels in Patientswith Diabetes Mellitus Complicated with Hypertension
文章编号:
1671-7414（2020）02-065-04
作者:
廖衍强
（珠海市斗门区侨立中医院, 广东珠海　519125）
Author(s):
LIAO Yan-qiang
（Qiaoli Hospital of Traditional Chinese Medicine Doumen District in Zhuhai,Guangdong Zhuhai 519125, China）
关键词:
胱抑素C; P 物质; 糖尿病; 高血压; 外周血
分类号:
R587.2；R446.112
DOI:
10.3969/j.issn.1671-7414.2020.02.019
文献标志码:
A
摘要:
目的　探讨糖尿病并发高血压患者外周血胱抑素-C(Cys C) 和P 物质(substance P,SP) 之间的关系。方法　将糖尿病患者按照是否发生高血压分为单纯糖尿病组（A 组）与并发高血压组（B 组），同时选取正常对照者作为C 组。比较三组人群的病历资料与外周血Cys C 和SP 等实验室指标，并进行相关的统计学分析。结果　A 组与B 组患者的平均HbAlc 水平、平均SP 水平与平均Cys C 水平均高于C 组，差异均有统计学意义。进一步进行snk-t 检验可见，A 组平均病程长于B 组患者（t=-8.753，P ＜ 0.000 1），平均HbAlc（t=-2.355，P=0.021），平均SP 水平（t=-6.164，P ＜ 0.0001）与平均Cys C 水平（t=-3.185，P=0.002）均低于B 组患者，差异有统计学意义。糖尿病患者高血压水平与SP 水平及Cys C 水平显著相关，但关系不密切（r=0.369，0.412，P＜ 0.5），高血压患者SP水平与Cys C 水平之间关系密切（r=0.526,P＞ 0.5），糖尿病患者高血压严重水平与病程、HbAlc，SP，CysC 相关。结论　糖尿病并发高血压患者外周血中Cys C和SP 会升高，且这种升高与高血压的程度正相关。

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备注/Memo

备注/Memo:
作者简介: 廖衍强（1975-），男，本科，副主任检验师，研究方向：医学检验，E-mail：xianzhiban766@163.com。收稿日期：2019-09-02修回日期：2019-10-26
更新日期/Last Update: 2020-04-30