[1]张 鹏,解 娟,刘文康,等.2009～2014年西安地区体检人群中肝炎病毒血清学检测回顾性分析[J].现代检验医学杂志,2015,30(04):135-136.[doi:10.3969/j.issn.1671-7414.2015.04.041]
　ZHANG Peng,XIE Juan,LIU Wen-kang,et al.Retrospective Analysis on Serological Detection of Hepatitis Viruses in Physical Examination Population in Xi'an During 2009～2014[J].Journal of Modern Laboratory Medicine,2015,30(04):135-136.[doi:10.3969/j.issn.1671-7414.2015.04.041]
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2009～2014年西安地区体检人群中肝炎病毒血清学检测回顾性分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第30卷
期数:
2015年04期
页码:
135-136
栏目:
检验与临床
出版日期:
2015-08-10

文章信息/Info

Title:
Retrospective Analysis on Serological Detection of Hepatitis Viruses in Physical Examination Population in Xi'an During 2009～2014
文章编号:
1671-7414(2015)04-135-03
作者:
张 鹏1; 解 娟2; 刘文康2; 王 华2; 李 玲2
1.西电集团医院检验科,西安 710077;
2.陕西省人民医院检验科,西安 710068
Author(s):
ZHANG Peng1; XIE Juan2; LIU Wen-kang2; WANG Hua2; LI Ling2
1.Department of Clinical Laboratory,Xi'an XD Group Hospital, Xi'an 710077,China;
2.Department of Clinical Laboratory, Shaanxi Provincial People's Hospital,Xi'an 710068,China
关键词:
体检人群;  肝炎病毒;  血清学;  回顾性分析
分类号:
R521.6; R392.11
DOI:
10.3969/j.issn.1671-7414.2015.04.041
文献标志码:
A
摘要:
目的 回顾性分析陕西省西安地区体检人群中各型肝炎病毒血清学流行情况。方法 利用酶联免疫吸附试验(ELISA)检测2009～2014年陕西省西安地区体检者血清中甲型肝炎病毒(HAV)抗体IgM,乙型肝炎病毒表面抗原(HBsAg),丙型肝炎病毒(HCV)抗体IgG,丁型肝炎病毒(HDV)抗体IgM,戊型肝炎病毒(HEV)抗体IgM和IgG。结果 1 315例体检者血清中HAV IgM阳性率为0.15%(2/1 315); 109 965例体检者血清中HBsAg阳性率为2.83%(3 360/109 965),HBsAg阳性率总体呈下降趋势(χ2=63.070,P=0.001); 各年度之间男性体检者血清中HBsAg阳性率无显著性差异(χ2=4.804,P=0.441),而各年度之间女性体检者血清中HBsAg总体阳性率逐年下降(χ2=18.046,P=0.003),男性体检者血清中HBsAg阳性率明显高于女性(χ2=126.9,P=0.000); 41 898例体检者血清中HCV抗体阳性率为0.79%(333/41 898),HCV抗体阳性率逐年下降(χ2=18.380,P=0.003); 1 079例体检者血清中未检测出丁型肝炎病毒抗体IgM; 1 195例体检者血清中HEV IgM阳性率为0.25%(3/1 195),而HEV IgG阳性率为3.93%(47/1 195)。结论 2009～2014年体检者中肝炎病毒感染以HBV和HCV为主,而且呈总体下降趋势,为陕西省西安地区各型肝炎病毒血清学流行情况提供了资料和防控依据。
Abstract:
Objective To investigate retrospective analysis on serological detection of hepatitis viruses inphysical examination population.Methods Hepatitis A virus(HAV)IgM,HBsAg,HCV IgG,HDV IgM,HEV IgM and HEV IgG were detected by ELISAassay in physical examination population during 2009～2014.ResultsThe positive rate of HAV IgM was 0.15%(2/1 315)in 1 315 physicalexaminees and that of HBsAg was 2.83%(3 360/109 965)in 109 965 ones during 2009～2014.The positive rates of HBsAg decreased trend in the last 6 years in general(χ2=63.070,P=0.001).There was no significant difference for HBsAg positive rate among male physical examinees in last six years(χ2=4.804,P=0.441),but the positive rate of HBsAg in female population decreased trend in the last 6 years in general(χ2=18.046,P=0.003),moreover the positive rate of HBsAg in male popolation was significantly higher than that in female ones(χ2=126.9,P=0.000).The positive rate of HCV IgG was 0.79%(333/41 898)in 41 898 physical examinees during 2009～2014 and that decreasedtrend in last 6 years(χ2=18.380,P=0.003).There was no HDV IgM detected in 1 079 physical examinees serum.The positive rate of HEV IgM and IgG were 0.25%(3/1 195)and 3.93%(47/1 195)respectively in 1 195 physical examinees.Conculsion The physical examination population during 2009～2014 were mainly infected by HBV and HCV and the infection rate decreased trendly in last 6 years,which provided important data for epidemiology of serological hepatitis viruses in Shaanxi provice.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金资助项目(NO.81272856)。
作者简介:张 鹏(1976-),男,本科,主管检验技师,研究方向:免疫学检验技术,Tel:13991909037。
通讯作者:李 玲(1964-),女,硕士,主任检验技师,研究方向:肿瘤分子生物学,Tel:13193368899。
更新日期/Last Update: 2015-08-10