[1]刘　云,孙静芳,马　萍.外周血血细胞参数在急性主动脉夹层与急性心肌梗死鉴别中的价值[J].现代检验医学杂志,2021,36(01):132-135.[doi:10.3969/j.issn.1671-7414.2021.01.033]
　LIU Yun,SUN Jing-fang,MA Ping.Value of Peripheral Blood Cell Parameters in Differentiating Acute Aortic Dissection from Acutemyocardial Infarction[J].Journal of Modern Laboratory Medicine,2021,36(01):132-135.[doi:10.3969/j.issn.1671-7414.2021.01.033]
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外周血血细胞参数在急性主动脉夹层与急性心肌梗死鉴别中的价值()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第36卷
期数:
2021年01期
页码:
132-135
栏目:
检验与临床
出版日期:
2021-02-05

文章信息/Info

Title:
Value of Peripheral Blood Cell Parameters in Differentiating Acute Aortic Dissection from Acutemyocardial Infarction
文章编号:
1671-7414（2021）01-132-04
作者:
刘　云; 孙静芳; 马　萍
(徐州医科大学附属医院检验科，江苏徐州 221002)
Author(s):
LIU Yun;  SUN Jing-fang;  MA Ping
（Department of Clinical Laboratory, the Affiliated Hospital of Xuzhou Medical College, Jiangsu Xuzhou 221002, China）
关键词:
单核细胞; 平均血小板体积 /血小板; 急性主动脉夹层; 急性心肌梗死
分类号:
R543.5；R542.22；R446.11
DOI:
10.3969/j.issn.1671-7414.2021.01.033
文献标志码:
A
摘要:
目的　探讨外周血血细胞参数在急性主动脉夹层（ acute aortic dissection, AAD）与急性心肌梗死（ acute myocardial infarction ,AMI）鉴别诊断中的价值。方法　回顾性分析 2019年 1~9月就诊于徐州医科大学附属医院急诊科并于入院后完善相关检查确诊为 AAD的患者 30例，AMI患者 30例，及同期健康体检者 20例外周血血细胞参数水平变化，利用 ROC曲线评估相关参数的诊断鉴别价值。结果　与 AMI组相比较， AAD组单核细胞（ monocyte，MON）和血小板平均体积 /血小板比值（ MPP）水平较高，血小板（ platelet，PLT）、血小板平均体积（ mean platelet volume， MPV）水平较低，差异均有统计学意义（ t=-2.363~3.890, 均 P<0.05）；与健康对照组相比， AAD组白细胞（ white blood cell，WBC）、中性粒细胞（ neutrophils，NEU）、MON，中性粒细胞 /淋巴细胞比值（ NLR）、血小板分布宽度（ Platelet distribution width，PDW）和 MPP均升高，淋巴细胞（ lymphocyte，LYM）、PLT和 MPV均降低，差异有统计学意义（t=-5.283~5.565,均 P<0.05）。MON，PLT，MPV和 MPP对 AAD和 AMI鉴别诊断的 ROC曲线下面积（ Area under curve, AUC）分别为 0.662，0.753，0.652和 0.664，联合 MON和 MPP的 AUC为 0.749，联合 MON，PLT和 MPV的 AUC为 0.872，四项联合检测的 AUC为 0.874；与单项指标检测相比四项联合检测 AUC最大，敏感度为 80.00%，特异度为 86.67%。结论　应用 MON+PLT+MPV+MPP四项联合检测鉴别诊断 AAD与 AMI优于单项指标检测，有望在临床推广应用。

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备注/Memo

备注/Memo:
作者简介：刘云（1989-），女 , 硕士 , 医师 , 研究方向为临床检验诊断，E-mail:liuyun11220704@163.com。
通讯作者：马萍，教授，主治医师，E-mail:Pingma62@yahoo.com.cn。
更新日期/Last Update: 2021-02-05