[1]吴红光,杨文东.围产期孕妇生殖道B族链球菌感染与耐药性分析[J].现代检验医学杂志,2016,31(01):104-107.[doi:10.3969/j.issn.1671-7414.2016.01.030]
　WU Hong-guang,YANG Wen-dong.Group B Streptococcus Infection in Vaginal Tract of Perinatal Pregnant Women and Drug Resistance Analysis[J].Journal of Modern Laboratory Medicine,2016,31(01):104-107.[doi:10.3969/j.issn.1671-7414.2016.01.030]
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围产期孕妇生殖道B族链球菌感染与耐药性分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第31卷
期数:
2016年01期
页码:
104-107
栏目:
论著
出版日期:
2016-01-25

文章信息/Info

Title:
Group B Streptococcus Infection in Vaginal Tract of Perinatal Pregnant Women and Drug Resistance Analysis
作者:
吴红光1; 杨文东2
1.东营市人民医院,山东东营 257091; 2.利津县第二人民医院,山东东营 257447
Author(s):
WU Hong-guang1; YANG Wen-dong2
1.the Second People's Hospital of Dongying,Shandong Dongying257091,China; 2.the Second People's Hospital of Lijin,Shandong Dongying 257447,China
关键词:
B族链球菌;  围产期孕妇;  带菌率;  药敏试验
分类号:
R378.12; R446.5
DOI:
10.3969/j.issn.1671-7414.2016.01.030
文献标志码:
A
摘要:
目的 通过分析围产期孕妇生殖道B族链球菌(GBS)的感染与耐药性,为临床医师制定有效的预防和治疗措施提供依据。方法 2013年1月～2015年2月,对795例围产期孕妇生殖道分泌物进行GBS培养鉴定与药敏试验,把结果进行统计学分析。结果 795例孕妇中共检出GBS携带者256例,带菌率为32.2%。<30岁组(28.9%)与≥30岁组(42.3%)的带菌率差异具有统计学意义(χ2=19.095,P<0.01)。GBS阳性者与GBS阴性者的临床症状发生率(18.8% vs 8.0%)差异具有统计学意义(χ2=39.514,P<0.01)。10种抗菌药物(万古霉素、利奈唑胺、青霉素、氨苄西林、头孢曲松、呋喃妥因、左旋氧氟沙星、克林霉素、红霉素及四环素)耐药率分别为:0,0,0.6%,3.1%,6.6%,9.6%,21.9%,23.8%,29.9%及58.1%; D-抑菌圈试验阳性率为23.9%。结论 该区围产期孕妇GBS带菌率较高,且高龄者易于感染; 围产期孕妇感染GBS对万古霉素、利奈唑胺、青霉素、氨苄西林、头孢曲松及呋喃妥因敏感率高。
Abstract:
Objective To provide evidences which are for clinicians to formulate effective prevention and treatment measures by analyzing the perinatal pregnant women vaginal group B streptococcus(GBS)infection and adverse pregnancy outcomes.Methods From January 2013 to February 2015,the vaginal secretions were sampled from 795 cases of perinatalpregnant women for culture identification of GBS,the final results were statistical analyzed.Results In the 795 pregnant women cases,there were 256 GBS carriers cases,the carrier rate was 32.2%.There was statistically significance(χ2=19.095,P<0.01)between less than 30 years oldgroup(28.9%)and greater than or equal to 30 years old group(42.3%).The different incidence rate of clinical symptoms between GBS negative cases and GBSpositive cases(18.8% vs 8.0%)was also had statistically significance(χ2=39.514,P<0.01).The antimicrobial resistant rates of ten kinds of antibacterial drugs(vancomycin,linezolid,penicillin,ampicillin,ceftriaxone,nitrofurantoin,levofloxacin,clindamycin,erythromycin and tetracycline)was 0,0,0.6%,3.1%,6.6%,9.6%,21.9%,23.8%,29.9% and 58.1% respectively.The positive rate of D-bacteriostatic ring experiment was 23.9%.Conclusion The carrier rate of perinatal pregnant women GBS was higherin this region,and the elderly were easier to be infected.Perinatal pregnant women infected with GBS to vancomycin and rina thiazole amine and penicillin andampicillin and ceftriaxone and with nitrofurantoin because of the sensitive rateis high.

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备注/Memo

备注/Memo:
作者简介:吴红光(1970-),男,硕士,副主任技师,检验科副主任,主要从事临床检验工作。 通讯作者:杨文东(1963-),男,学士,副主任技师,主要从事临床检验、病理诊断与技术工作,E-mail:yangwendong007@126.com。
更新日期/Last Update: 2016-01-20