[1]靳庆娥,苏建荣,乌姗娜,等.2015年北京地区成人急性呼吸道感染9种病原体IgM抗体检测分析[J].现代检验医学杂志,2017,32(02):157-159.[doi:10.3969/j.issn.1671-7414.2017.02.044]
　JIN Qing-e,SU Jian-rong,WU Shan-na,et al.Analysis of IgM Antibody of Nine Acute Respiratory Tract Infection Pathogens in Adults During 2015 in Beijing Area[J].Journal of Modern Laboratory Medicine,2017,32(02):157-159.[doi:10.3969/j.issn.1671-7414.2017.02.044]
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2015年北京地区成人急性呼吸道感染9种病原体IgM抗体检测分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第32卷
期数:
2017年02期
页码:
157-159
栏目:
检验与临床
出版日期:
2017-03-25

文章信息/Info

Title:
Analysis of IgM Antibody of Nine Acute Respiratory Tract Infection Pathogens in Adults During 2015 in Beijing Area
文章编号:
1671-7414(2017)02-157-03
作者:
靳庆娥; 苏建荣; 乌姗娜; 辛德莉
首都医科大学附属 北京友谊医院检验科，北京 100050
Author(s):
JIN Qing-e; SU Jian-rong; WU Shan-na; XIN De-li
Department of Clinical Laboratory， Affiliated Beijing Friendship Hospital，Capital Medical University，Beijin g 100050，China
关键词:
呼吸道感染; 间接免疫荧光法; IgM抗体
分类号:
R37；R446.5
DOI:
10.3969/j.issn.1671-7414.2017.02.044
文献标志码:
A
摘要:
目的 探讨成人急性呼吸道感染(ARI)患者病原体感染状况 ，分析其流行病学特征。方法 收集2015年2 700例ARI患者血清，用间接免疫荧光法检测嗜肺军团菌血清1型(LP1)，肺炎支原体(MP)，Q热立克次体(COX)，肺炎衣原体(CP)，腺病毒(ADV)，呼吸道合胞病毒(RSV)，甲型和乙型流感病毒(INFA，INFB)以及副流感病毒1，2和3型(PIVs)等9种病原体IgM抗体。结果 共检测到620例阳性患者，感染率为22.97%；感染率由高到低依次为MP，LP1，INFB，COX，CP，PIVs，INFA，ADV和RSV。其中混合感染占17.58%(109/620)，以LP1+MP混合感染最常见。若以月份划分，11月份病原体感染率最高，4月份感染率最低(χ2=31.288，P＜0.01)；不同病原体流行季节也不同。男性患者感染率显著高于女性(χ2=6.402，P=0.011)。若以年龄段划分，40岁的青壮年感染率最高(χ2=9.094，P=0.059)。门诊病人与住院患者相比感染率无差异(χ2=0.114，P=0.736)。结论 MP，LP1和INFB是2015年北京地区成人呼吸道感染的主要病原体。
Abstract:
Objective To determine pathogens and epidemiolo gical characteristics of adults with acute respiratory infection (ARI) in Beijin g area．Methods During 2015，a total of 2 700 cases of AR I were sampled and detected for 9 respiratory pathogens including Legionella pne umophila type1 (LP1)，mycoplasma pneumoniae (MP)，qrickettsia (COX)，chlamydia p neumoniae (CP)，adenovirus (ADV)，respiratory syncytial virus (RSV)，influenza v irus type A and B (INFA，IFVB) and parainfluenza viruses type1，2 and 3 (PIVs) u sing indirect fluorescence immunoassay．Results A total o f 620 cases of ARI were tested positive with positive rate of 22.97% (620/2 700 )．MP had the highest prevalence followed by LP1，INFB，COX，CP，PIVs，INFA，ADV and RSV in turn．There were 109 cases found mixed infection with the proportion of 17.58% (109/620)．Mixed infection of LP1 along with MP was the most common pattern．The highest detection rate of pathogens was observed in November，where as the lowest in April in terms of months (χ2= 31.288，P＜0.01)．Differ ent pathogens had distinct prevalent features．The prevalence of male was signif icant higher than that of female (χ2=6.402，P=0.011)．As for stratifica ted by age，the middle-aged people had the highest infection rate (χ2=9.0 94，P=0.059)．There was no significant difference between the out- and in-p atient in terms of infection rate (χ2=0.114，P=0.736)．Concl usion MP，LP1 and INFB accounted for ARI of adults in Beijing area d uring 2015．

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备注/Memo

备注/Memo:
基金项目：国家自然科学基金资助项目(No. 81271890)。
作者简介:靳庆娥(1981-)，女，博士，助理研究员，主要从事病 毒分子诊断，Tel：010-63138577，E-mail：jinqinge@163.com。
通讯作者:辛德莉，女，主任医师，硕士生导师，主要从事支原体感染及病原微生物耐药机制研究，Tel：010-63138552，E-mail：xindl48@126.com。
更新日期/Last Update: 2017-04-10