[1]袁 巧,白静静,袁 喆,等.2013～2015年重症监护病房的呼吸机相关性肺炎病原学构成及耐药性分析[J].现代检验医学杂志,2017,32(03):45-48.[doi:10.3969/j.issn.1671-7414.2017.03.012]
　YUAN Qiao,BAI Jing-jing,YUAN Zhe,et al.Analysis of Distribution and Drug Resistance of Isolated Pathogen s for Ventilator-Associated-Pneumonia in ICU from 2013 to 2015[J].Journal of Modern Laboratory Medicine,2017,32(03):45-48.[doi:10.3969/j.issn.1671-7414.2017.03.012]
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2013～2015年重症监护病房的呼吸机相关性肺炎病原学构成及耐药性分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第32卷
期数:
2017年03期
页码:
45-48
栏目:
论著
出版日期:
2017-05-25

文章信息/Info

Title:
Analysis of Distribution and Drug Resistance of Isolated Pathogen s for Ventilator-Associated-Pneumonia in ICU from 2013 to 2015
文章编号:
1671-74 14(2017)03-045-04
作者:
袁 巧1; 白静静2; 袁 喆1; 周泓羽1
1.重庆医科大学附属第一医院医院感染管理科，重庆 400016；
2.陕西省人民医院，西安 710068
Author(s):
YUAN Qiao1; BAI Jing-jing2; YUAN Zhe1; ZHOU Hong -yu1
1.Department of Hospital Infection， the First Affiliated Hospital of Chongqing Medical University，Chongqing 4 00016，China；
2.Shaanxi Provincial Peoples’ Hospital，Xi’an 710068，China
关键词:
耐药性; 呼吸机相关性肺炎
分类号:
R563.1；R446.5
DOI:
10.3969/j.issn.1671-7414.2017.03.012
文献标志码:
A
摘要:
目的 分析重症监护病房(ICU)2013～2015年呼吸机相关性 肺炎的病原学构成及耐药性变化，为临床抗菌治疗提供方向。方法 收集2013年1月～2015年12月ICU诊断为呼吸机相关性肺炎的病例资料，统计病例病原菌总体 构成及主要病原菌的耐药率，采用卡方检验比较三年的病原学构成比，秩和检验比较主要病 原菌的耐 药情况。结果 2013年～2015年，共有177例呼吸机相关性肺炎感染 患 者，分离菌株192株，以革兰氏阴性菌为主，占90.6%，三年病原学构成比的比较差异无统 计学意义(χ2=2.372，P=0.668>0.05)。比较主要病原菌鲍曼不动杆菌、铜绿假单 胞菌、金黄色葡萄球菌的药敏分析情况，其中鲍曼不动杆菌不同年份药敏分析比较差异有统 计学意义。结论 2013～2015年呼吸机相关性肺炎病原菌以革兰氏阴 性菌为主，特别是鲍曼不动杆菌。呼吸机相关性肺炎感染病例检出的鲍曼不动杆菌耐药很严 重，应针对鲍曼不动杆菌引起的呼吸机相关性肺炎足够、恰当用药。
Abstract:
Objective To analyze the changes of distributio n and drug resistance of isolated pathogens for ventilator-associated-pneumoni a (VAP) in seven intensive care units from January 2013 to December 2015，so tha t provides information for clinical antibiotic treatment．Methods Collected the patient records diagnosed with VAP to get the distributio n and drug resistance of isolated pathogens for VAP in ICU from January 2013 to De cember 2015．Compared the distribution of isolated pathogens for VAP among thr ee year with Chi-square tests，and compared the drug resistance of main isolate d pathogens with Nonparametric tests．Results 177 patients were diagnosed with VAP from January 2013 to December 2015．A total of 192 strai ns of pathogens were isolated from the VAP patients in ICU．Among which the gram -negative bacteria were dominant．It took up 90.6%．There was no significant s tatistical difference for the distribution of pathogens (χ2=2.372，P=0 .668>0.05)．Analyzed the drug resistance rate and trends for the primary patho gens like Acinetobacter Bauman，Pseudomonas aeruginosa and Staphylococcus aureus，among which，the drug resistance of Acinetobacter Bauman　from 201 3 to 2015 made statistical difference．Conclusion The maj or pathogen isolated from VAP patients was gram-negative bacteria from January 2013 to December 2015，especially for Acinetobacter Bauman．Drug resistance of Acinetobacter Bauman was serious．Should administrated appropriate to treat the VAP infection resulted from Acinetobacter Bauman．

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备注/Memo

备注/Memo:
基金项目：陕西省科学技术研究发展计划项目，编号：2014KRM99- 02。
作者简介：袁 巧(1981-)，女，硕士，主治医师，主要从事医院 感染管理方面研究，E-mail：903947242@qq.com。
通讯作者：白静静，女，硕士，主管护师，E-mail：15558826@q q.com。
更新日期/Last Update: 2017-06-25