[1]张艳双,刘 静,万 楠,等.耐碳青霉烯类肠杆菌科(CRE)耐药分子机制及控制流行的应对策略[J].现代检验医学杂志,2019,34(02):1-4.[doi:10.3969/j.issn.1671-7414.2019.02.001]
 ZHANG Yan-shuang,LIU Jing,WAN Nan,et al.Molecular Mechanism of Carbapenem-Resistant Enterobacteriaceae(CRE)Resistance and Coping Strategies for Controlling Epidemics[J].Journal of Modern Laboratory Medicine,2019,34(02):1-4.[doi:10.3969/j.issn.1671-7414.2019.02.001]
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耐碳青霉烯类肠杆菌科(CRE)耐药分子机制及控制流行的应对策略()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第34卷
期数:
2019年02期
页码:
1-4
栏目:
述评
出版日期:
2019-05-11

文章信息/Info

Title:
Molecular Mechanism of Carbapenem-Resistant Enterobacteriaceae(CRE)Resistance and Coping Strategies for Controlling Epidemics
文章编号:
1671-7414(2019)02-001-04
作者:
张艳双刘 静万 楠栾 亮
(中国人民解放军北部战区总医院检验医学中心,沈阳 110000)
Author(s):
ZHANG Yan-shuangLIU JingWAN NanLUAN Liang
(Laboratory Medicine Center,General Hospital of Northern TheaterCommand ofthe Chinese People's Liberation Army,Shenyang 110000,China)
关键词:
耐碳青霉烯类肠杆菌科细菌 分子机制 预防控制措施
分类号:
R378.2; R446.5
DOI:
10.3969/j.issn.1671-7414.2019.02.001
文献标志码:
A
摘要:
耐碳青霉烯类肠杆菌科细菌(CRE)世界范围内扩散传播且越来越流行,其引起的相关性感染的死亡率高达70%。在过去20年间,碳青霉烯类抗生素大量应用导致耐碳青霉烯类肠杆菌科细菌迅速增加且耐药性已得到认可。由于其治疗方法有限、易感染性以及高死亡率,使得CRE在医疗环境中的传播逐渐成为全球重大的公共卫生威胁。因此,为避免这种灾难性流行病的发生,需要做好准备计划,积极采取有效的预防控制措施来阻止这些细菌的传播。在文中作者综述了CRE菌株的发展、耐药分子机制,并根据现状提出预防控制措施,以遏制CRE的流行。
Abstract:
Carbapenem-resistant Enterobacteriaceae(CRE)spreads and spreads worldwide,with a mortality rate of 70% for related infections.Over the past 20 years,the extensive use of carbapenem antibiotics has led to a rapid increase in carbapenem-resistant Enterobacteriaceae and resistance has been recognized.Due to its limited treatment,susceptibility and highmortality,the spread of CRE in the medical environment has become a major public health threat worldwide.Therefore,in order to avoid the occurrence of sucha catastrophic epidemic,it is necessary to prepare a plan and actively take effective preventive and control measures to prevent the spread of these bacteria.In the article,the authors reviewed the development of CRE strains,the molecular mechanisms of drug resistance,and proposed preventive and control measures based on the status quo to curb the prevalence of CRE.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:辽宁省自然科学基金(NO:20180550457)作者简介:张艳双(1992-),女,硕士在读,研究方向:耐碳青霉烯肠杆菌科机制研究,E-mail:350005801@qq.com。 张艳双,刘 静,万 楠,栾 亮(中国人民解放军北部战区总医院检验医学中心,沈阳 110000) 收稿日期:2019-01-10 修回日期:2019-03-19
更新日期/Last Update: 2019-04-30