[1]王艳霞,肖景华,李亚妮,等.孕妇血清铁、锌微量元素与妊娠期高血压疾病的关系[J].现代检验医学杂志,2019,34(02):130-131.[doi:10.3969/j.issn.1671-7414.2019.02.033]
 WANG Yan-xia,XIAO Jing-hua,LI Ya-ni,et al.Study on the Relationship between Serum Iron and Zinc Trace Elementsin Pregnant Women and Hypertensive Disorders in Pregnancy[J].Journal of Modern Laboratory Medicine,2019,34(02):130-131.[doi:10.3969/j.issn.1671-7414.2019.02.033]
点击复制

孕妇血清铁、锌微量元素与妊娠期高血压疾病的关系()
分享到:

《现代检验医学杂志》[ISSN:/CN:]

卷:
第34卷
期数:
2019年02期
页码:
130-131
栏目:
检验与临床
出版日期:
2019-05-11

文章信息/Info

Title:
Study on the Relationship between Serum Iron and Zinc Trace Elementsin Pregnant Women and Hypertensive Disorders in Pregnancy
文章编号:
1671-7414(2019)02-130-03
作者:
王艳霞肖景华李亚妮郭 娜米 阳冯卫红
(西北妇女儿童医院,西安 710000)
Author(s):
WANG Yan-xiaXIAO Jing-huaLI Ya-niGUO NaMI YangFENG Wei-hong
(Northwest Women and Children's Hospital,Xi'an 710000,China)
关键词:
妊娠期高血压疾病 血清锌 血清铁 微量元素
分类号:
R714.246; R446.112
DOI:
10.3969/j.issn.1671-7414.2019.02.033
文献标志码:
A
摘要:
目的 通过测定妊娠期高血压疾病孕妇与正常孕妇血清微量元素铁、锌水平,研究血清铁、锌水平与妊娠期高血压疾病的相关性。方法 在2018年1~10月于西北妇女儿童医院住院患者中选取研究对象,研究组为妊娠期高血压疾病孕妇55例,对照组为无并发症正常孕妇61例,用原子吸收光谱法测定两组孕妇血清微量元素铁、锌水平,分析血清铁、锌水平与妊娠期高血压疾病的相关性。结果 ①血清铁水平:研究组1.37±0.78μg/ml vs 对照组0.92±0.43 μg/ml,差异有统计学意义(t=1.98,P<0.05); ②血清锌水平:研究组0.67±0.18μg/ml vs 对照组0.77±0.15 μg/ml,差异有统计学意义(t=1.98,P<0.05)。结论 ①孕妇血清高铁负荷,低锌水平可能与妊娠期高血压疾病有相关性; ②孕期应监测血清铁、锌水平,合理补充微量元素。
Abstract:
Objective To study the correlation between serum iron and zinc levels in pregnant women and hypertensive disorders in pregnancy.Methods From January 2018 to October 2018,55 pregnantwomen with gestational hypertension were randomly selected as the study group and 61 normal pregnant women as the control group.The levels of serum iron and zinc were determined by atomic absorption spectrometry.The differences of iron and zinc levels between the two groups were analyzed and compared.Results The level of serum trace element iron in the study group was higher than that in the control group(1.37±0.78 μg/ml vs 0.92±0.43 μg/ml),the difference was statistically significant(t=1.98,P<0.05),while thelevel of serum zinc was lower than that in the control group(0.67±0.18 μg/ml vs 0.77±0.15 μg/ml),the difference was statistically significant(t=1.98,P<0.05).Conclusion ①Serum iron load and low zinc level could be related to hypertensive disorders in pregnancy.②Serum iron andzinc levels should be monitored during pregnancy,and trace elements should besupplemented reasonably.

参考文献/References:

[1] 中华医学会妇产科学分会妊娠期高血压疾病学组.妊娠期高血压疾病诊治指南(2015)[J].中华妇产科杂志,2015,50(10):721-728. Group of Hypertensive Diseases of Pregnancy,Branch of Obstetrics and Gynecology,Chinese Medical Association.Guidelines for the diagnosis and treatment of hypertensive diseases of pregnancy(2015)[J].Chinese Journal of Obstetrics and Gynecology,2015,50(10):721-728.
[2] 杨本善,舒杨,文江平,等.北京市老年人群血清铁、总铁结合力参考区间调查[J].现代检验医学杂志,2017,32(2):138-140. YANG Benshan,SHU Yang,WEN Jiangping,et al.Investigation for thereference intervals of serum iron and total iron binding capacity among 60+ years people in Beijing[J].Journal of Modern Laboratory Medicine,2017,32(2):138-140.
[3] 蔡洁,张惠迪,杨丽琛.人体铁生理需要量研究进展[J].卫生研究,2018,47(1):170-172. CAI Jie,ZHANG Huidi,YANG Lichen.Research progress on physiological iron requirements of human body[J].Journal of Hygiene Research,2018,47(1):170-172.
[4] CUI Jiefen,LI Yinping,YU Peng.A novel low molecular weight Enteromorpha polysaccharide-iron(III)complex and its effect on rats with iron deficiencyanemia(IDA)[J].International Journal of Biological Macromolecules,2018,108:412-418.
[5] BERTOLI S R,MARQUES V B,ROSSI E M,et al.Chronic iron overload inducesvascular dysfunction in resistance pulmonary arteries associated with right ventricular remodeling in rats[J].Toxicology Letters,2018,295(1):296-306.
[6] 刘洋,徐梅,蒋英,等.血清微量元素及抗氧化能力指标与妊娠期高血压疾病的关系分析[J].海南医学院学报,2016,22(6):574-576,579. LIU Yang,XU Mei,JIANG Ying,et al.Relationship between serum trace elements and antioxidant capacity indexes in women of hypertensive disorders complicating pregnancy[J].Journal of Hainan Medical University,2016,22(6):574-576,579.
[7] BRUNACCI F,ROCHA V S,DE CARLI E,et al.Increased serum iron in preeclamptic women is likely due to low hepcidin levels[J].Nutrition Research,2018,53:32-39.
[8] SULIBURSKA J,SKRYPNIK K,SZULI SKA M,et al.Effect of hypotensive therapy combined with modified diet or zinc supplementation on biochemical parametersand mineral status in hypertensive patients[J].Journal of Trace Elements inMedicine and Biology,2018,47:140-148.
[9] 孟建芳.妊娠不同时期补充微量元素及叶酸对妊娠结局的影响[J].中国妇幼保健,2016,31(23):4954-4956. MENG Jianfang.Effects of supplementary trace elements and folic acid on pregnancy outcomes at different stages of pregnancy[J].Maternal and Child Health Care of China,2016,31(23):4954-4956.
[10] 庄小瑜,郭焕仪,王丹婵.600例孕妇微量元素检测结果分析[J].牡丹江医学院学报.2017,38(3):108-110.ZHUANG Xiaoyu,GUO Huanyi,WANG Danchan.Analysis of trace elements in600 pregnant women[J].Journal of Mudanjiang Medical University,2017,38(3):108-110.

相似文献/References:

[1]郭彩娇,杨红玲,高 飞,等.孕20周前妊娠期高血压孕妇常规检验指标的新临床意义研究[J].现代检验医学杂志,2018,33(01):95.[doi:10.3969/j.issn.1671-7414.2018.01.001]
 GUO Cai-jiao,YANG Hong-ling,GAO Fei,et al.Study on the New Clinical Significance of Routine Indexes in Pregnant Women with HDP before 20 Weeks of Pregnancy[J].Journal of Modern Laboratory Medicine,2018,33(02):95.[doi:10.3969/j.issn.1671-7414.2018.01.001]
[2]侯书利,张金玲,李 燕,等.妊娠期高血压病患者血清DNMT1 mRNA 和LncRNA UCA1 水平表达与妊娠结局的关系[J].现代检验医学杂志,2024,39(05):47.[doi:10.3969/j.issn.1671-7414.2024.05.009]
 HOU Shuli,ZHANG Jinling,LI Yan,et al.Relationship between the Expression of Serum DNMT1 mRNA and LncRNA UCA1 Levels and Pregnancy Outcome in Patients with Hypertensive Disorder Complicating Pregnancy[J].Journal of Modern Laboratory Medicine,2024,39(02):47.[doi:10.3969/j.issn.1671-7414.2024.05.009]

备注/Memo

备注/Memo:
研究基金项目:陕西省科学技术厅资助项目(2018SF-068),项目编号:S2018-YF-YBSF-0372。 作者简介:王艳霞(1983-),女,硕士,主治医师,研究方向:孕期保健及产科危重症,E-mail:1202624546@qq.com。 通讯作者:冯卫红,女,副主任医师,主要从事妊娠期糖尿病及产科危重症工作,E-mail:467774830@qq.com。 收稿日期:2018-08-24 修回日期:2019-02-23 页码131+136
更新日期/Last Update: 2019-04-30