参考文献/References:
[1] LI Xingwang, NI Xin, QIAN Suyun, et al. Chinese guidelines for the diagnosis and treatment of hand, foot and mouth disease (2018 edition)[J]. World Journal of Pediatrics, 2018, 14(5): 437-447.
[2] YANG Yang, CONG Haolong, DU Ning, et al. Mitochondria redistribution in enterovirus A71 infected cells and its effect on virus replication[J]. Virologica Sinica, 2019, 34(4): 397-411.
[3] YANG Xiaoxia, SHUI Xiaochuan, DAI Xiaoqing, et al. PLAC8 promotes EV71 infected inflammatory lesion by disturbing Th-cell-related cytokines release in neonatal mouse [J]. Virology,2021,564:39-45.
[4] LI Yi, LI Shengrui, QIU Yinfeng, et al. Circulating FGF21 and GDF15 as biomarkers for screening, diagnosis, and severity assessment of primary mitochondrial disorders in children[J]. Front Pediatr,2022,10:851534.
[5] LEHTONEN J M, AURANEN M, DARIN N, et al. Diagnostic value of serum biomarkers FGF21 and GDF15 compared to muscle sample in mitochondrial disease [J]. Journal of Inherited Metabolic Disease, 2021, 44(2): 469-480.
[6] KAUR N, GARE S R, RUIZ-VELASCO A, et al. FGF21/FGFR1-β-KL cascade in cardiomyocytes modulates angiogenesis and inflammation under metabolic stress[J]. Heliyon, 2023, 9(4): e14952.
[7] KATO E T, MORROW D A, GUO Jianping, et al. Growth differentiation factor 15 and cardiovascular risk:individual patient meta-analysis[J]. European Heart Journal, 2023, 44(4): 293-300.
[8] 李玄丹, 李材忠, 唐永婕, 等.老年ARDS 患者血清FGF-21,GDF-15 及PTX-3 表达水平及其与病情评估和预后的相关性研究[J]. 现代检验医学杂志, 2022,37(4): 188-192. LI Xuandan, LI Caizhong, TANG Yongjie, et al. Expression levels of serum FGF-21, GDF-15 and PTX-3 in elderly patients with ARDS and their correlation with disease evaluation and prognosis [J]. Journal of Modern Laboratory Medicine, 2022, 37(4): 188-192.
[9] YIN Dan, YAN Xiaofang, BAI Xueke, et al. Prognostic value of growth differentiation factors 15 in acute heart failure patients with preserved ejection fraction[J]. ESC Heart Failure, 2023, 10(2): 1025-1034.
[10] DAVIS R L, LIANG C, SUE C M. A comparison of current serum biomarkers as diagnostic indicators of mitochondrial diseases[J]. Neurology, 2016, 86(21): 2010-2015.
[11] RILEY L G, NAFISINIA M, MENEZES M J, et al. FGF21 outperforms GDF15 as a diagnostic biomarker of mitochondrial disease in children[J]. Molecular Genetics and Metabolism, 2022, 135(1): 63-71.
[12] KANG Kai, XU Pengfei, WANG Mengxia, et al. FGF21 attenuates neurodegeneration through modulating neuroinflammation and oxidant-stress [J].Biomed Pharmacother, 2020,129:110439.
[13] LENG Yan, WANG Junyu, WANG Zhifei, et al. Valproic acid and other HDAC inhibitors upregulate fgf21 gene expression and promote process elongation in glia by inhibiting HDAC2 and 3 [J]. Int J Neuropsychoph, 2016,19(8): pyw035.
[14] LUAN H H, WANG A, HILLIARD B K, et al. GDF15 is an Inflammation-Induced central mediator of tissue tolerance[J]. Cell, 2019, 178(5): 1231-1244.e11.
[15] R?HLE A, WIEDENMANN N, FENNELL J T, et al. Interleukin-6 as surrogate marker for imaging-based hypoxia dynamics in patients with head-and-neck cancers undergoing definitive chemoradiation-results from a prospective pilot trial[J]. European Journal of Nuclear Medicine and Molecular Imaging, 2022, 49(5): 1650-1660.
[16] 王秋云, 严敏, 程珍, 等.肿瘤及血液病患者血清sTRAIL 表达及与IL-6 和Hepcidin 水平的相关性研究[J]. 现代检验医学杂志, 2021, 36(1): 58-60, 64. WANG Qiuyun, YAN Min, CHENG Zhen, et al.Study of the expression of the serum sTRAIL, and its correlation with levels of serum IL-6 and hepcidin in the patients with the tumor and hematological diseases[J]. Journal of Modern Laboratory Medicine, 2021, 36(1): 58-60, 64.
[17] ZHU Lei, YIN Hong, QIAN Tong, et al. Distinct expression and clinical value of aquaporin 4 in children with hand, foot and mouth disease caused by enterovirus 71[J]. Journal of Medical Virology, 2022, 94(2): 587-593.
[18] LEE J Y, SON M, KANG Jinhan, et al. Serum interleukin-6 levels as an indicator of aseptic meningitis among children with enterovirus 71-induced hand, foot and mouth disease[J]. Postgraduate Medicine, 2018, 130(2): 258-263.
[19] TAVENIER J, RASMUSSEN L J H, ANDERSEN A L, et al. Association of GDF15 with inflammation and physical function during aging and recovery after acute hospitalization: a longitudinal study of older patients and Age-Matched controls[J]. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 2021, 76(6): 964-974.
[20] YANG Pinni, ZHU Zhengbao, SHI Mengyao, et al. Association of serum growth differentiation factor-15 levels with the risks of death and vascular events in patients with ischemic stroke: The role of diabetes[J].Nutrition Metabolism and Cardiovascular Diseases, 2022, 32(3): 616-623.
[21] WANG Bei, ZHANG Chongyang, YU Congci, et al. Enterovirus 71 induces INF2 cleavage via activated caspase-2 in infected RD cells [J]. Front Microbiol,2021,12:684953.