[1]刘欢欢,刘 爽,朱亚荣,等.宏基因捕获法在感染性疾病诊断中应用的最新研究进展[J].现代检验医学杂志,2026,41(01):195-199.[doi:10.3969/j.issn.1671-7414.2026.01.038]
 LIU Huanhuan,LIU Shuang,ZHU Yarong,et al.Latest Research Progress on the Application of Metagenomic Capture in the Diagnosis of Infectious Diseases[J].Journal of Modern Laboratory Medicine,2026,41(01):195-199.[doi:10.3969/j.issn.1671-7414.2026.01.038]
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宏基因捕获法在感染性疾病诊断中应用的最新研究进展()

《现代检验医学杂志》[ISSN:/CN:]

卷:
第41卷
期数:
2026年01期
页码:
195-199
栏目:
综述
出版日期:
2026-01-15

文章信息/Info

Title:
Latest Research Progress on the Application of Metagenomic Capture in the Diagnosis of Infectious Diseases
文章编号:
1671-7414(2026)01-195-05
作者:
刘欢欢刘 爽朱亚荣吴境宇李永霞
西安金域医学检验所有限公司,西安 710002
Author(s):
LIU HuanhuanLIU ShuangZHU YarongWU JingyuLI Yongxia
Xi’an Jinyu Medical Laboratory Group Co. Ltd, Xi’an 710002, China
关键词:
感染宏基因捕获法病原检测
分类号:
R446.7
DOI:
10.3969/j.issn.1671-7414.2026.01.038
文献标志码:
A
摘要:
感染性疾病是指由病原微生物引起的一类疾病,是急危重症患者死亡的主要原因之一。传统的微生物鉴定方法因灵敏度低、特异性差且耗时长,已难以满足临床诊断和治疗的需求。宏基因捕获法(MetaCAP)以其高特异性、高灵敏度、广谱检测和精准诊断等优点,在感染性疾病诊断中展现出重要的应用价值。该文综述了MetaCAP在感染性疾病诊断中的最新研究进展,旨在为感染性疾病的临床诊断及精准治疗提供新的思路与理论支持。
Abstract:
Absrtact:Infectious diseases, caused by pathogenic microorganisms, are one of the leading causes of death among critically ill patients. Traditional microbiological identification methods, with their relatively low sensitivity, specificity, and time-consuming nature, are increasingly inadequate for meeting the clinical demands of diagnosis and treatment. Metagenomic capture (MetaCAP), owing to its high sensitivity, specificity, broad-spectrum detection, and precise diagnostic capabilities, has demonstrated significant potential in the diagnosis of infectious diseases. This review highlights the latest advances in the application of MetaCAP for infectious disease diagnosis, aiming to provide novel insights and theoretical support for the clinical diagnosis and precision treatment of infectious diseases.

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备注/Memo

备注/Memo:
作者简介:刘欢欢(1995-),女,硕士,临床检验技术师,研究方向:感染检测技术,E-mail:Huanhuan_Liu5@163.com。
通讯作者:李永霞(1986-),女,主管检验技师,研究方向:感染性疾病诊疗新技术。
更新日期/Last Update: 2026-01-15