[1]刘振国a,王婷b,卢晓娥a.CVVHDF联合HP治疗蜂蜇伤患者临床生化指标的变化研究[J].现代检验医学杂志,2015,30(05):115-117.[doi:10.3969/j.issn.1671-7414.2015.05.035]
　LIU Zhen-guoa,WANG Tingb,LU Xiao-ea.Analysis of the Changes of Clinical and Biochemical Indexes in Treatment of Continuous Venovenous Hemodiafiltration Combined with Hemoperfusion in Patients with Bee Stings[J].Journal of Modern Laboratory Medicine,2015,30(05):115-117.[doi:10.3969/j.issn.1671-7414.2015.05.035]
点击复制

CVVHDF联合HP治疗蜂蜇伤患者临床生化指标的变化研究()
分享到：

《现代检验医学杂志》[ISSN:/CN:]

卷:
第30卷
期数:
2015年05期
页码:
115-117
栏目:
论著
出版日期:
2015-12-10

文章信息/Info

Title:
Analysis of the Changes of Clinical and Biochemical Indexes in Treatment of Continuous Venovenous Hemodiafiltration Combined with Hemoperfusion in Patients with Bee Stings
作者:
刘振国a; 王婷b; 卢晓娥a
陕西省人民医院 西安交通大学第三附属医院 a.重症医学科；b.西院干部一病区，西安710068
Author(s):
LIU Zhen-guoa; WANG Tingb; LU Xiao-ea
a.Intensive Care Unit；b.Cadres Ward，Shaanxi Provincial People’s Hospital， the Third Affiliated Hospital of Medical School，Xi’an Jiaotong University， Xi’an 710068，China
关键词:
磷酸肌酸激酶同工酶; 总胆红素; 丙氨酸氨基转移酶; 天门冬氨酸氨基转移酶; 肌红蛋白; 尿素氮; 肌酐; 连续性静静脉血液透析滤过; 血液灌流; 蜂蜇伤
分类号:
R459.5；R446.112
DOI:
10.3969/j.issn.1671-7414.2015.05.035
文献标志码:
A
摘要:
目的探讨连续性静脉血液透析滤过(CVVHDF)联合血液灌流(HP)治疗蜂蜇伤患者中临床血清磷酸肌酸激酶同工酶(CK-MB)、总胆红素(TBil)、丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、肌红蛋白(Mb)、尿素氮(BUN)和肌酐(Scr)生化指标的变化研究及CVVHDF联合HP在蜂蜇伤中的临床应用价值。方法选取陕西省人民医院25例蜂蜇伤患者，分为常规组(局部处理、抗感染、抗过敏、抑制炎症反应、营养心肌、保肝保肾、营养支持等综合治疗)10例和CVVHDF联合HP治疗组(上述常规综合治疗+ CVVHDF联合HP)15例，比较两组治疗前和治疗后24，48 h的血清CK-MB，TBil，ALT，AST，Mb，BUN和Scr。结果常规组经48 h治疗后上述生化指标与治疗前比较变化不明显(P＞0.05)，CVVHDF联合HP治疗组经24，48 h治疗后上述生化指标与治疗前比较有所降低，差异有统计学意义(P＜0.05)。结论CVVHDF联合HP治疗蜂蜇伤患者早期血清CK-MB，TBil，ALT，AST，Mb，BUN和Scr生化指标水平明显降低，能尽早恢复患者各脏器功能，是临床治疗蜂蜇伤患者的有效手段，具有重要临床应用价值。
Abstract:
ObjectiveTo analyze the changes of serum creatine kinase isoenzyme (CK-MB)，total bilirubin (TBil)，alanine aminotransferase (ALT)，aspartate amino transferase (AST)，myoglobin (Mb)，usea nitrogen (BUN) and creatinine (Scr) in treatment of continuous venovenous hemodiafiltration (CVVHDF) combined with hemoperfusion (HP) in patients with bee stings．MethodsThe 25 cases of bee stings were collected，they were divided into conventional treatment group included 10 cases and the group of CVVHDF combined HP treatment included 15 cases．Conventional therapy included partial treatment，anti-infection，antianaphylaxis，inhibiting the inflammatory reaction，nourishing cardiac muscle，protecting of liver and kidney，nutritional support and so on，the therapy of CVVHDF combined with HP group included conventional therapy and continuous CVVHDF combined with HP treatment．Compared with the level of CK-MB，TBil，ALT，AST，Mb，BUN and Scr in before and after the first day，the second day treatment of two groups．ResultsThe above clinical and biochemical indexes were no obvious changes after 48h treatment in conventional treatment group compared with before treatment (P＞0.05)，while were reduced after treatment in the group of CVVHDF combined with HP treatment compared with before treatment (P＜0.05)．ConclusionCVVHDF combined with HP in patients with bee stings was an effective means．Not only could reduce clinical and biochemical indexes but also recovery of multiple organ function in the early phase，that has important value in clinical application．

参考文献/References:

［1］夏敬彪，刘先哲．蜂蜇伤研究进展［J］．国外医学(内科学分册)，2006，33(3)：127-130． Xia JB，Liu XZ．Research Process of Bee Stings［J］．Foreign Medicine(Fascicule of Internal Medicine)，2006，33(3)：127-130．
[2]Viswanathan S，Muthu V，Singh AP，et al．Middle ce-rebral artery infarct following multiple bee stings［J］．J Stroke Cerebrovasc Dis，2012，21(2)：148-150．
[3]Friedman LS，Modi P，Liang SL，et al．Analysis of hymenoptera stings reported to the illinois poison center［J］．J Med Entomol，2010，47(5)：907-912．
[4]张华，陈华，李永兴，等．心肌损伤标志物的联合测定在急性心肌梗死中的应用［J］．现代检验医学杂志，2007，22(5)：104-105． Zhang H，Chen H，Li YX，et al．The application of simultaneous determination of myocardial injury markers in Acute Myocardial Infarction［J］．Journal of Modern Laboratory Medicine，2007，22(5)：104-105．
[5]曾雅莉，马清峰，熊微，等．不同病期慢性HBV感染者肝功能、HBV-DNA与HBV-M模式的关系［J］．国际检验医学杂志，2015，36(4)：433-435． Zeng YL，Ma QF，Xiong W，et al．Relationships between HBV-M patterns and liver function，HBV-DNA in patients with chronic HBV infection of different stages［J］．International Journal of Laboratory Medicine，2015，36(4)：433-435．
[6]李婷，张婷，方绕红，等．UmALB血清CysC，Cr和BUN水平对GDM早期肾损伤的诊断价值［J］．中国卫生检验杂志，2015，25(3)：385-386，404． LI T，Zhang T，Fang RH，et al．The diagnostic value of UmALB，serum CysC，Cr and BUN levels of early renal damage in GDM［J］．Chinese Journal of Health Laboratory Technology，2015，25(3)：385-386，404．
[7]谢华，肖敏．群蜂蛰伤治疗临床研究进展［J］．临床急诊杂志，2014，15(7)：445-447． Xie H，Xiao M．The clinical research advances of massive wasp stings［J］．Journal of Clinical Emergency(China)，2014，15(7)：445-447．
[8]曹平，刘琼．血液净化联合血塞通注射液治疗蜂蜇伤并多器官功能障碍综合征的临床研究［J］．中国中医急症，2013，22(3)：358-360． Cao P，Liu Q．The clinical study of the blood purification combined with xuesaitong injection on multiple organ dysfunction syndrome caused by bee sting［J］．Journal of Emergency in Traditional Chinese Medicine，2013，22(3)：358-360．
[9]张莹，王敬，陈昕，等．血液灌流联合血液透析早期治疗重症野蜂蜇伤的临床观察［J］．医学综述，2013，19(7)：1311-1313． Zhang Y，Wang J，Chen X，et al．Clinical observation：hemoperfusion combined with hemodialysis in early treatment of severe hornet stings［J］．Medical Recapitulate，2013，19(7)：1311-1313．

相似文献/References:

[1]郝树彬,孙洪厚,孙秀会,等.氧化酶法和钒酸盐法测定血清胆红素的方法比较[J].现代检验医学杂志,2017,32(01):113.[doi:10.3969/j.issn.1671-7414.2017.01.031]
　HAO Shu-bin,SUN Hong-hou,SUN Xiu-hui,et al.Developed for the Determination of Serum Bilirubin between Oxidase Method and Vanadate Oxidation Method[J].Journal of Modern Laboratory Medicine,2017,32(05):113.[doi:10.3969/j.issn.1671-7414.2017.01.031]

备注/Memo

备注/Memo:
作者简介：刘振国(1983-)，女，医学硕士，主治医师，从事急危重症病研究工作，Tel：13484622631，E-mail：379740078@qq.com。
更新日期/Last Update: 1900-01-01