[1]王芳胜,熊敦勇,寇辉,等.血清AFP，CEA，CA-199与TAP在肝癌诊断中的应用价值[J].现代检验医学杂志,2015,30(05):148-150.[doi:10.3969/j.issn.1671-7414.2015.05.047]
　WANG Fang-sheng,XIONG Dun-yong,KOU Hui,et al.Application Value of Serum AFP，CEA，CA-199 and TAP in the Diagnosis of Hepatocellular Carcinoma[J].Journal of Modern Laboratory Medicine,2015,30(05):148-150.[doi:10.3969/j.issn.1671-7414.2015.05.047]
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血清AFP，CEA，CA-199与TAP在肝癌诊断中的应用价值()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第30卷
期数:
2015年05期
页码:
148-150
栏目:
检验与临床
出版日期:
2015-12-10

文章信息/Info

Title:
Application Value of Serum AFP，CEA，CA-199 and TAP in the Diagnosis of Hepatocellular Carcinoma
作者:
王芳胜; 熊敦勇; 寇辉; 任光玉; 张剑锋; 朱皓皞
中国人民解放军第九四医院，江西南昌330002
Author(s):
WANG Fang-sheng; XIONG Dun-yong; KOU Hui; REN Guang-yu; ZHANG Jian-feng; ZHU Hao-hao
the Ninety-fourth Hospital of People’s Liberation Army，Jiangxi Nanchang 330002，China
关键词:
异常糖链糖蛋白; 甲胎蛋白; 癌胚抗原; 糖链抗原199; 肝癌
分类号:
R735.7；R730.43
DOI:
10.3969/j.issn.1671-7414.2015.05.047
文献标志码:
A
摘要:
目的探讨血清甲胎蛋白(AFP)，癌胚抗原(CEA)，糖链抗原199(CA-199)与糖链糖蛋白(TAP)在肝癌诊断中的应用价值。方法收集69例肝癌患者为研究对象，比较各肿瘤标记物(TM)的敏感度、特异度及阳性率等指标。结果肝癌确诊患者中，TAP，CEA，AFP，CA-199及联合检测敏感度分别为88.40%，40.60%，53.6%，34.80%和95.60%；阳性率分别为68.40%，40.54%，46.84%，34.23%和75.67%。四项肿瘤标记物联合检测敏感度(95.60%)和阳性率(75.67%)明显高于其他各单项检测指标，特别是在继发性肝癌中，联合检测起到明显弥补作用。结论四项肿瘤标记物联合检测优于AFP，CEA，CA-199和TAP各单项检测，是一个很好的肝癌筛查方法。
Abstract:
ObjectiveTo explore the application value of serum CEA，AFP，CA-199 and TAP in the diagnosis of liver cancer．MethodsIt collected 69 hospitalized patients of liver cancer．And researched the TM detection sensitivity，specificity，positive rate and other indicators．ResultsFrom diagnosed HCC patients found that TAP，CEA，AFP，CA-199 and combined detection sensitivity were 88.40%，40.60%，53.6%，34.80% and 95.60% respectively．The positive rate of those were 68.40%，40.54%，46.84%，34.23% and 75.67% respectively．It was obviously that four TM were more sensitive (95.60%) and positive rate (75.67%) for individual detection than other indicators．ConclusionThe joint detection of four TM were more sensitive to detect the individual than AFP，CEA，CA-199 and TAP．So can consider it as a better liver cancer screening method．

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备注/Memo

备注/Memo:
作者简介：王芳胜(1989-)，男，大学本科，从事分子病理学工作，E-mail：wfs1023466250@163.com。 通讯作者：朱皓皞(1979-)，女，医学硕士，副主任医师，从事临床分子病理学诊断。
更新日期/Last Update: 1900-01-01