[1]汪 阔,徐忠意,何家花.外周血NLR,PLR和LMR水平分析在儿童流感病毒与疱疹性咽峡炎感染鉴别诊断中的临床意义[J].现代检验医学杂志,2021,36(02):136-139.[doi:doi:10.3969/j.issn.1671-7414.2021.02.032]
 WANG Kuo,XU Zhong-yi,HE Jia-hua.Clinical Significance of Peripheral Blood NLR,PLR and LMR Level Analysis in Differential Diagnosis of Influenza Virus Infection and Herpangina in Children[J].Journal of Modern Laboratory Medicine,2021,36(02):136-139.[doi:doi:10.3969/j.issn.1671-7414.2021.02.032]
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外周血NLR,PLR和LMR水平分析在儿童流感病毒与疱疹性咽峡炎感染鉴别诊断中的临床意义()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第36卷
期数:
2021年02期
页码:
136-139
栏目:
检验与临床
出版日期:
2021-04-30

文章信息/Info

Title:
Clinical Significance of Peripheral Blood NLR,PLR and LMR Level Analysis in Differential Diagnosis of Influenza Virus Infection and Herpangina in Children
文章编号:
1671-7414(2021)02-136-04
作者:
汪 阔徐忠意何家花
(商洛市中心医院,陕西商洛726000)
Author(s):
WANG Kuo XU Zhong-yi HE Jia-hua
( the Central Hospital of Shangluo City, Shaanxi Shangluo 726000,China)
关键词:
血小板和淋巴细胞计数比值儿童流感病毒疱疹性咽峡炎
分类号:
R373.1;R446.11
DOI:
doi:10.3969/j.issn.1671-7414.2021.02.032
文献标志码:
A
摘要:
目的 探讨外周血全血细胞分析中的三项指标在鉴别儿童流感病毒和疱疹性咽峡炎的临床意义。方法 收集2019年11月1日 ~2020年1月31日商洛市中心医院就诊的有上呼吸道感染症状患儿189例,采用胶体金法检测甲乙流感病毒抗原,采集患儿初诊时外周血进行全血细胞分析。研究组纳入甲型流感85例,乙型流感43例。对照组纳入甲乙流感病毒阴性的疱疹性咽峡炎患儿61例。分别比较三组之间中性粒细胞和淋巴细胞计数比值(NLR)、血小板和淋巴细胞计数比值(PLR)、淋巴细胞和单核细胞计数比值(LMR)水平,并对结果进行统计学分析。结果 流感组与对照组的三项感染指标水平比较,差异均有统计学意义(F=11.51,13.00和29.37,均P<0.05)。进一步对甲流组和乙流组进行比较,两组之间的NLR,PLR和LMR水平差异有统计学意义(均P<0.05)。三项感染指标的ROC曲线下面积 (area under the curve,AUC)分别为0.723,0.837和0.725,当NLR截点为3.77时,灵敏度和特异度分别为60%和73%;PLR截点为147.83时,灵敏度和特异度分别为71.1%和80% ;LMR截点为2.57时,灵敏度和特异度分别为71.8%和65%。结论 在甲乙型流感病毒感染与疱疹性咽峡炎的辅助鉴别诊断中PLR优于NLR和LMR两项指标。

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备注/Memo

备注/Memo:
作者简介:汪阔(1988-),男,本科,主管技师,主要研究方向:临床微生物学检验,E-mail :wagkuo@126.com。
通讯作者:何家花(1987-),女,在读硕士,主管技师,主要研究方向:临床微生物学检验,E-mail :745249229@qq.com。
更新日期/Last Update: 2021-04-10