[1]王晶,王欢欢,张绍城.四川省绵阳地区健康儿童维生素A,D和E营养水平的分析研究[J].现代检验医学杂志,2018,33(03):144-147.[doi:10.3969/j.issn.1671-7414.2018.03.037]
　WANG Jing,WANG Huan-huan,ZHANG Shao-cheng.Study on the Nutritional Levels of Fat-Soluble Vitamin A,D and E in Healthy Children in Mianyang of Sichuan Provunce[J].Journal of Modern Laboratory Medicine,2018,33(03):144-147.[doi:10.3969/j.issn.1671-7414.2018.03.037]
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四川省绵阳地区健康儿童维生素A,D和E营养水平的分析研究()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第33卷
期数:
2018年03期
页码:
144-147
栏目:
检验与临床
出版日期:
2018-07-17

文章信息/Info

Title:
Study on the Nutritional Levels of Fat-Soluble Vitamin A,D and E in Healthy Children in Mianyang of Sichuan Provunce
文章编号:
1671-7414(2018)03-144-04
作者:
王晶; 王欢欢; 张绍城
绵阳市中心医院检验科,四川绵阳 621000
Author(s):
WANG Jing; WANG Huan-huan; ZHANG Shao-cheng
Department of Clinical Laboratory,Mianyang Center Hospital,Sichuan Mianyang 621000,China
关键词:
儿童;  维生素A;  25羟基维生素D;  维生素E
分类号:
R723.2
DOI:
10.3969/j.issn.1671-7414.2018.03.037
文献标志码:
A
摘要:
目的 了解四川省绵阳地区1～16岁健康儿童维生素A,25-羟基维生素D[(25-(OH)D)]和维生素E水平。方法 以2017年1～12月在绵阳市中心医院儿保门诊接受健康体检的750例健康儿童作为研究对象,按年龄分为3组:婴幼儿1～3岁481例,学龄前(3～6岁)儿童132例,青少年(6～16岁)137例,采用液相色谱串联质谱(LC-MS/MS)法检测血清维生素A,25-(OH)D和维生素E水平。结果血清维生素A,25-(OH)D和维生素E平均水平分别为0.45±0.25 mg/L,27.27±11.38 ng/mL及9.18±5.75 mg/L。血清维生素A水平无年龄差异(χ2=1.002,P=0.606),血清25-(OH)D水平(χ2=6.843,P=0.033)与维生素E水平(χ2=14.922,P=0.001)在不同年龄组差异有统计学意义。维生素A构成比在年龄上差异有统计学意义(χ2=35.471,P<0.01),在各年龄组中均存在过量情况,且随着年龄增长呈增加趋势; 血清25-(OH)D构成比在年龄上差异有统计学意义(χ2=20.900,P<0.01),其缺乏率和不足率随着儿童年龄增长呈增加趋势; 维生素E构成比无年龄差异(χ2=7.054,P=0.133),其在各年龄组缺乏率与不足率均较明显,其中学龄前组总体缺乏最为严重,达74.2%。结论 四川省绵阳地区1～16岁健康儿童维生素A,25-(OH)D和维生素E的营养状况不容乐观,应提高对脂溶性维生素的监测、预防意识,增加富含维生素A,25-(OH)D和维生素E的食物摄入,必要时在医生指导下及时补充维生素制剂。
Abstract:
Abstract:Objective To investigate the serum levels of vitamin A,25-hydroxy vitamin D [25-(OH)D],viyamin E levels in healthy children aged 1～16 years in Mianyang,Sichuan province.Methods From January to December 2017 in the Outpatient Department of Mianyang CentralHospital,750 healthy children health examination were chosed as the research object group.They were divided into 3 groups according to age:infants aged 1～3years 481 cases,preschool children(3～6 years old)132 children and teenagers(6～16 years old)137 cases.Their serum vitamin A,25-(OH)D and vitamin E levels were measured by Liquid chromatography tandem mass spectrometry(LC-MS/MS).Results The vitamin A,25-(OH)D,vitamin E in serum was0.45±0.25 mg/L,27.27±11.38 ng/ml and 9.18±5.75 mg/L.Stratified analysis showed serum levels of different age had no difference(χ2=1.002,P=0.606),The differences of serum 25-(OH)D(χ2=6.843,P=0.033)and vitamin E(χ2=14.922,P=0.001)were statistically significant.The ratio ofvitamin A composition was statistically significant in age(χ2=35.471,P<0.01).There was an overdose in all age groups and increased with age.The ratio of 25-(OH)D in serum was statistically significant(χ2=20.900,P<0.01),as the age of children grew,the rate of deficiency and insufficiency showed an increasing trend.There was no age difference in vitamin E constituent ratio(χ2=7.054,P=0.133),and the deficiency and insufficiency rate of each age group were more obvious.Among them,the age group 3～6 years old was the most serious,reaching 74.2%.Conclusion The nutritional status of vitamin A,25-(OH)D and vitamin E in 1～16 years old children in Mianyang of Sichuan is not optimistic.It is necessary to improve the monitoring of fat-soluble vitamins and improve the awareness of prevention.And increase the intake of foods rich in vitamin A,25-(OH)D,vitamin E,supplementation of vitamin preparations in time under the guidance of a doctor.

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备注/Memo

备注/Memo:
基金项目: 四川省卫生和计划生育委员会资助项目(No.16PJ189); 绵阳市中心医院资助项目(No.2015YJ01; No.2015YJ02)。 作者简介:王 晶(1990-),女,本科,初级检验师,主要从事临床生物化学工作。
更新日期/Last Update: 2018-04-16