[1]景双艳,王晓宁,魏莲花,等.金黄色葡萄球菌表面蛋白Ebh致病性的研究进展[J].现代检验医学杂志,2019,34(02):156-159.[doi:10.3969/j.issn.1671-7414.2019.02.040]
　JING Shuang-yan,WANG Xiao-ning,WEI Lian-hua,et al.Advances in Research on Pathogenicity ofStaphylococcus Aureus Surface Protein Ebh[J].Journal of Modern Laboratory Medicine,2019,34(02):156-159.[doi:10.3969/j.issn.1671-7414.2019.02.040]
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金黄色葡萄球菌表面蛋白Ebh致病性的研究进展()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第34卷
期数:
2019年02期
页码:
156-159
栏目:
综述
出版日期:
2019-05-11

文章信息/Info

Title:
Advances in Research on Pathogenicity ofStaphylococcus Aureus Surface Protein Ebh
文章编号:
1671-7414(2019)02-156-04
作者:
景双艳1; 王晓宁1; 魏莲花2; 李可可1; 林赋桂3; 余 甜1; 谢 越1; 闫亚芳3
(1.甘肃中医药大学,兰州730000; 2.甘肃省人民医院,兰州 730000; 3.宁夏医科大学,银川 750000)
Author(s):
JING Shuang-yan1; WANG Xiao-ning1; WEI Lian-hua2; LI Ke-ke1; LIN Fu-gui3; YU Tian1; XIE Yue1; YAN Ya-fang3
(1.Gansu University of Chinese Medicine,Lanzhou 730000,China; 2.Gansu Povincial People's Hospital,Lanzhou 730000,China; 3.Ningxia Medical University,Yinchuan 750000,China)
关键词:
金黄色葡萄球菌;  Ebh蛋白;  致病性
分类号:
R378.11; R446.5
DOI:
10.3969/j.issn.1671-7414.2019.02.040
文献标志码:
A
摘要:
细菌感染一直以来都是全球医学专家共同面临的一个难题,特别是当越来越多种类的耐药致病菌的出现。金黄色葡萄球菌既是共生菌又是人类病原体,是引起人类感染性疾病的重要病原菌之一,能够引起局部化脓感染,包括肺炎、伪膜性肠炎、心包炎,甚至败血症、脓毒症等全身感染。有研究发现,在金黄色葡萄球菌表面存在着一种巨蛋白,称为Ebh(ECMbinding protein homologue)。Ebh作用于生物膜的黏附、聚集,与其致病性密切相关。该文将对其进行综述。
Abstract:
Bacterial infections have long been a problem faced by medical experts around the world,especially as more and more types of resistant pathogens emerge.Staphylococcus aureus is both a commensal and a human pathogen,and is one of the important pathogens causing human infectious diseases.It can cause localized purulent infections,including pneumonia,pseudomembranous colitis,pericarditis,and even systemic infections such as sepsis andsepsis.Studies have found that there is a giant protein on the surface of Staphylococcus aureus,called Ebh(ECMbinding protein homologue).Ebh acts on theadhesion and aggregation of biofilms and is closely related to its pathogenicity.This article will review the following sections.

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备注/Memo

备注/Memo:
基金项目:甘肃省自然科学基金(17JR5RA035)。 作者简介:景双艳(1991-),女,硕士在读,从事微生物研究,E-mail:960112698@qq.com。 通讯作者:魏莲花(1965-),主任检验师,硕士生导师,E-mail:weilianhua0199@sina.com。 收稿日期:2019-01-03 修回日期:2019-01-27
更新日期/Last Update: 2019-04-30