[1]刘爱胜,房笃智,姚 伟.深圳宝安区孕期夫妇红细胞葡萄糖-6-磷酸脱氢酶缺乏现状情况调查[J].现代检验医学杂志,2015,30(03):157-158.[doi:10.3969/j.issn.1671-7414.2015.03.048]
　LIU Ai-sheng,FANG Du-zhi,YAO Wei.Present Situation Investigation of Red Blood Cells Glucose-6-Phosphate Dehydrogenase Dificiency of Pregnancy Couple in Baoan District of Shenzhen[J].Journal of Modern Laboratory Medicine,2015,30(03):157-158.[doi:10.3969/j.issn.1671-7414.2015.03.048]
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深圳宝安区孕期夫妇红细胞葡萄糖-6-磷酸脱氢酶缺乏现状情况调查()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第30卷
期数:
2015年03期
页码:
157-158
栏目:
检验与临床
出版日期:
2015-06-10

文章信息/Info

Title:
Present Situation Investigation of Red Blood Cells Glucose-6-Phosphate Dehydrogenase Dificiency of Pregnancy Couple in Baoan District of Shenzhen
文章编号:
1671-7414(2015)03-157-03
作者:
刘爱胜1; 房笃智2; 姚 伟3
1.深圳市龙华新区人民医院检验科,广东深圳 518109;
2.深圳市宝安区人民医院检验科,广东深圳 518001;
3.深圳市宝安区松岗人民医院检验科,广东深圳 518101
Author(s):
LIU Ai-sheng1; FANG Du-zhi2; YAO Wei3
1.Department of Clinical Laboratory,Shenzhen Longhua New District People's Hospital,Guangdong Shenzhen 518109,China;
2.Department of Clinical Laboratory,Shenzhen Baoan District People's Hospital,Guangdong Shenzhen 518001,China;
3.Department o
关键词:
孕期夫妇;  葡萄糖-6-磷酸脱氢酶;  缺乏;  现状调查
分类号:
R446.112
DOI:
10.3969/j.issn.1671-7414.2015.03.048
文献标志码:
A
摘要:
目的 了解宝安区孕期夫妇红细胞葡萄糖-6-磷酸脱氢酶(G6PD)缺乏的现状,以便引起社会的重视。方法 收集2013年2月～11月来深圳市宝安区人民医院产前门诊进行孕检的宝安区育龄夫妇共6 574例,其中男性3 192例,女性3 382例,分别采集静脉血用EDTA抗凝混匀,采用改良红细胞葡萄糖-6-磷酸脱氢酶定量比值法测定抗凝全血中G6PD/6PGD的比值,以比值＜1.0判为G6PD缺乏。结果 3 192例男性受检者中,G6PD缺乏的176例,3 382例孕妇受检者中检出135例,检出率分别是5.51%和3.99%,总检出率为4.73%(311/6 574),G6PD缺乏率男性高于孕妇,G6PD缺乏男:女为1.30:1(176:135),两者之间差异有统计学意义(χ2=7.16,P＜0.05)。结论 宝安区孕期夫妇G6PD缺乏有较高的发生率,男性明显高于女性,应引起社会关注。孕期夫妇孕检时应提倡双方G6PD活性筛查,这对优生优育和保健母婴身体健康有着重要的意义。
Abstract:
Objective To understand red blood cells glucose-6-phosphate dehydrogenase(G6PD)dificiency of pregnancy couple in baoan district of Shenzhen,in order to draw the attention of society.MethodsCollected 6 574 cases of couples of child-bearing age(3 192 malesand 3 382 females),in Baoan District People's Hospital,from February to November 2013.Venous blood was collected using EDTA anticoagulant blending respectively,the improvement of red bloodcells and glucose-6-phosphate dehydrogenase quantitative ratio method to determine anticoagulant G6PD/6 PGD ratio in thewhole blood,with ratio ＜1.0 convicted of G6PD deficiency.Results3 192 cases of male subjects,G6PD deficient 176 cases,3 382 cases of pregnant women client detection of 135 cases in the detection rate were 5.51%and 3.99%,respectively,the total detection rate was 4.73%(311/6 574),G6PDlack of rate was higher than that of pregnant women,men G6PD lack of male:female was 1.30:1(176:135),the difference was statistically significant between(χ2=7.16,P＜0.05).Conclusion The baoan district couple G6PD lack had a higher incidence of pregnancy,men were significantlyhigher than women,should arouse attention.Couples pregnancy test during pregnancy should be advocated the G6PD activity screening,the eugenics and maternal and child health care has important significance.

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备注/Memo

备注/Memo:
基金项目:深圳市宝安区科技局基金资助,项目编号:2013126。
作者简介:刘爱胜(1973-),男,本科,学士,副主任技师,主要从事临床检验及血库工作,E-mail:curious1997@163.com。
更新日期/Last Update: 2015-06-10