[1]邵杰,杨玉东,朱红强,等.临床标本病原菌检测及耐药数据的回顾性分析研究[J].现代检验医学杂志,2015,30(06):113-115.[doi:10.3969/j.issn.1671-7414.2015.06.034]
　SHAO Jie,YANG Yu-dong,ZHU Hong-qiang,et al.Retrospective Analysis of the Pathogens and Drug Resistance of Clinical Specimens[J].Journal of Modern Laboratory Medicine,2015,30(06):113-115.[doi:10.3969/j.issn.1671-7414.2015.06.034]
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临床标本病原菌检测及耐药数据的回顾性分析研究()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第30卷
期数:
2015年06期
页码:
113-115
栏目:
检验与临床
出版日期:
2015-12-30

文章信息/Info

Title:
Retrospective Analysis of the Pathogens and Drug Resistance of Clinical Specimens
作者:
邵杰; 杨玉东; 朱红强; 樊建勇; 岳秀; 焦婕英
兵器工业521医院，西安710065
Author(s):
SHAO Jie; YANG Yu-dong; ZHU Hong-qiang; FAN Jian-yong; YUE Xiu; JIAO Jie-ying
the 521 Hospital of China North Industries Group Corporation，Xi’an 710065，China
关键词:
病原菌; 抗生素; 耐药; 回顾性分析
分类号:
R446.5
DOI:
10.3969/j.issn.1671-7414.2015.06.034
文献标志码:
A
摘要:
目的了解临床感染性病原菌的构成比及耐药性，为临床诊治和选择抗菌药物提供帮助。方法回顾性分析了2013年10月~2014年2月临床科室所采集的痰液、血液、胸腹腔积液、胆汁、尿液、前列腺液等标本762份进行的病原菌检测和药敏试验结果。结果培养鉴定出620株病原菌，其中大肠埃希菌处于感染的首位共156株(占25.16%)，金黄色葡萄球菌71株(占11.45%)，铜绿假单胞菌54株(占8.71%)，粪肠球菌40株(占6.45%)，白假丝酵母菌35株(占5.65%)。阳性球菌对替考拉宁和万古霉素的敏感性较高，阴性杆菌对哌拉西林/他唑巴坦、头孢哌酮/舒巴坦、亚胺培南的敏感性较高。结论临床送检标本的感染以大肠埃希菌、金黄色葡萄球菌和铜绿假单胞菌最为常见，多数对头孢菌素、青霉素、丁胺卡那霉素耐药，选择抗菌药物时应引起大家的重视。
Abstract:
ObjectiveTo understand clinical pathogenic infectious ratio and drug resistance level．MethodsAnalyzed 762 specimens of sputum，blood，pleural effusion，bile，urine，prostate fluid，etc．These specimens were collected by various departments from 10/2013 to 2/2014．ResultsThe infection of E．coli was still among the top of 156 strains (25.16%)，staphylococcus aureus 71 strains (11.45%)，pseudomonas aeruginosa 54 strains (8.71%)，enterococcus 40 strains (6.45%)，and white candida 35 strains (5.65%)．Positive coccus was highly sensitive to teicoplanin and vancomycin．Negative bacilli was highly sensitive to piperacillin/tazobactam sodium，cefoperazone/sulbactam sodium，and imipenem．ConclusionClinical infections in E．coli，staphylococcus aureus，and pseudomonas aeruginosa were the most common．There should be reasonable use of antibiotics，control infections within hospitals，and prevent new epidemic strains．

参考文献/References:

［1］朱俊民，曹兴华．2011～2013年医院感染菌群分布及耐药状况分析［J］．国际检验医学杂志，2015，36(7)：925-926，929． Zhu JM，Cao XH．Analysis of pathogenic bacterial distribution and drug resistance of hospital infection during 2011～2013［J］．Int J Lab Med，2015，36(7)：925-926，929．
[2]刘玉岭，汪玉龙，宋文，等．2015年综合医院临床分离病原菌分布及耐药性分析［J］．临床合理用药杂志，2015，8(5A)：3-5． Liu YL，Wang YL，Song W，et al．Distribution of pathogenic bacteria and resistance analysis in a hospital during 2015［J］．Chin J of Clinical Rational Drug Use，2015，8(5A)：3-5．
[3]叶应妩，王毓三，申子瑜．全国临床检验操作规程［S］．3版．南京：东南大学出版社，2006：761-861． Ye YW，Wang YS，Shen ZY．National guide to clinical laboratory procedures［S］．3th Ed．Nanjing：Publishing House of Southeast University，2006：761-861．
[4]李平，金炎，邵春红，等．住院患者感染病原菌和常用抗菌药物敏感性分析［J］．检验医学与临床，2011，12(6)：838-841． Li P，Jin Y，Shao CH，et al．Analyzation of the pathogenic bacteria and drug resistance in the patients inhospital［J］．Lab Med Clin，2011，12(6)：838-841．
[5]覃琼英，赖极隆，李健玲．细菌耐药性监测与临床抗生素的合理使用［J］．现代检验医学杂志，2007，22(3)：108-109． Qin QY，Lai JL，Li JL．Observation of the drug resistance and clinical uses of antibiotics［J］．J Mod Lab Med，2007，22(3)：108-109．
[6]涂海健，林群英，陈淑娟，等．莆田学院附属医院1 917株多重耐药菌检测分析［J］．中国预防医学杂志，2015，15(5)：387-390．Tu HJ，Lin QY，Chen SJ．et al．Analyzation of 1 917 Multi drug resistant bacteria in affiliated hospital of Putian college［Ｊ］．Chin Prev Med，2015，15(5)：387-390．
[7]李虹玲，刘文恩，张运丽，等．从临床标本中分离出的病原性细菌的分布及耐药性分析［J］．中国现代医学杂志，2015，25(10)：40-44． Li HL，Liu WE，Zhang YL．et al．Distribution and antibiotic resistance of pathogenic bacteria isolated from clinical sample［J］．China Journal of Modern Medicine，2015，25(10)：40-44．
[8]马列婷，王林川，于燕，等．西安地区不动杆菌产β-内酰胺酶与耐药关系的分析［J］．现代检验医学杂志，2008，23(6)：45-47． Ma LT，Wang LC，Yu Y．et al．Analysis on the β-lactamases-producing of Acinetobacter with drug resistance in Xi’an city［Ｊ］．J Mod Lab Med，2008，23(6)：45-47．
[9]朱柏珍，雷艳英，陈海英．正确解读细菌药敏报告与合理选择抗菌药物［J］．中国现代药物应用，2012，6(8)：86-88． Zhu BZ，Lei YY，Chen HY．Right understand the report of drug resistance and choose the suitable antibiotics［Ｊ］．Chin J Mod Drug Appl，2012，6(8)：86-88．
[10]李文月．细菌耐药监测与抗菌药物合理应用［J］．中国现代药物应用，2015，9(9)：147-150． Li WY．Observation of the drug resistance and suitable use of antibiotics［Ｊ］．Chin J Mod Drug Appl，2015，9(9)：147-150．

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备注/Memo

备注/Memo:
作者简介：邵杰(1981-)，女，硕士学位，主治医生，研究方向：呼吸系统疾病的临床诊治，E-mail：30466417@qq.com。
更新日期/Last Update: 1900-01-01