[1]安 娜,刘运双,陈 曦,等.儿童肺炎支原体感染与血清维生素D水平的相关研究[J].现代检验医学杂志,2016,31(02):117-119.[doi:10.3969/j.issn.1671-7414.2016.02.035]
　AN Na,LIU Yun-shuang,CHEN Xi,et al.Relationship of the Mycoplasma Pneumonia Infection and Vitamin D levels in Children[J].Journal of Modern Laboratory Medicine,2016,31(02):117-119.[doi:10.3969/j.issn.1671-7414.2016.02.035]
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儿童肺炎支原体感染与血清维生素D水平的相关研究()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第31卷
期数:
2016年02期
页码:
117-119
栏目:
检验与临床
出版日期:
2016-06-01

文章信息/Info

Title:
Relationship of the Mycoplasma Pneumonia Infection and Vitamin D levels in Children
作者:
安 娜; 刘运双; 陈 曦; 高 静
绵阳市中心医院检验科,四川绵阳 621000
Author(s):
AN Na; LIU Yun-shuang; CHEN Xi; GAO Jing
Department of Clinical Laboratory,Mianyang Central Hospital,Sichuan Mianyang 621000,China
关键词:
儿童;  肺炎支原体;  维生素D
分类号:
R375.2; R446.112
DOI:
10.3969/j.issn.1671-7414.2016.02.035
文献标志码:
A
摘要:
目的 探讨肺炎支原体(mycoplasma pneumonia,MP)感染与维生素D(Vitamin D,VitD)水平之间的相关性。方法 以2014年7～10月间就诊的650例0～13岁人群为研究对象,采用被动凝集法检测其MP的感染情况,采用电化学发光法测定血清中VitD水平。结果 研究对象的MP抗体阳性率为22.46%,MP抗体阳性组的VitD水平(中位数为28.06 ng/ml,范围为8.99～64.84 ng/ml)明显低于阴性组(中位数为32.48 ng/ml,范围为8.54～67.31 ng/ml),差异有统计学意义(U=-3.876,P=0.000); VitD减低组的MP抗体阳性率(27.86%)明显高于VitD正常组(18.38%),差异有统计学意义(χ2=8.222,P=0.004); MP与VitD呈负相关(r=-0.180,P=0.000)。结论 MP感染与VitD水平具有密切的相关性,MP感染可能导致VitD水平降低,VitD水平减低后也可能会导致MP感染。
Abstract:
Objective To investigate the relationship between mycoplasma pneumonia(MP)infection and vitamin D(VitD)levels.Methods Subjects in the study were 650 children aged from 0 to 13years old,passive agglutination method was used to measure the infection of mycoplasma pneumonia,and electrochemiluminescence assay was used to measure VitD in serum.Results MP antibody positive rate of the subjects in the study was 22.46%,the VitD levels of MP infected people(median=28.06ng/ml,8.99～64.84 ng/ml)were significantly lower and the uninfected ones(median=32.48 ng/ml,8.54～67.31 ng/ml),and the difference was statistically significant(U=-3.876,P=0.000).MP antibody positive rate of VitD reduce group(28.06%)was significantly higher than that in normal VitD group(18.38%),and the difference was statistically significant(χ2=8.222,P=0.004).VitD levels were negatively correlated with MP(r=-0.180,P=0.000).Conclusion The MP infection was closely related to VitD levels,MP infection may lead to reduce VitD levels,and lower the VitD levels may alsolead to MP infection.

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备注/Memo

备注/Memo:
作者简介:安 娜(1988-),女,硕士,检验师,研究方向:临床免疫学,Tel:18281403139,E-mail:anna1596@126.com。
更新日期/Last Update: 2016-02-20