[1]刘佳丽,王 薇,何法霖,等.全国566家临床实验室血清降钙素原室内质量控制不精密度调查与分析[J].现代检验医学杂志,2018,33(02):139-142.[doi:10.3969/j.issn.1671-7414.2018.02.001]
　LIU Jia-li,WANG Wei,HE Fa-lin,et al.Investigation and Analysis of the Coefficient of Variation of Internal Quality Control of the Serum Procalcitonin in 566 Laboratories in China[J].Journal of Modern Laboratory Medicine,2018,33(02):139-142.[doi:10.3969/j.issn.1671-7414.2018.02.001]
点击复制

全国566家临床实验室血清降钙素原室内质量控制不精密度调查与分析()
分享到：

《现代检验医学杂志》[ISSN:/CN:]

卷:
第33卷
期数:
2018年02期
页码:
139-142
栏目:
质量控制·实验室管理
出版日期:
2018-04-05

文章信息/Info

Title:
Investigation and Analysis of the Coefficient of Variation of Internal Quality Control of the Serum Procalcitonin in 566 Laboratories in China
文章编号:
1671-7414(2018)02-139-04
作者:
刘佳丽; 王 薇; 何法霖; 钟 堃; 袁 帅; 张志新; 杜雨轩; 王治国
北京医院 国家老年医学中心 卫生部临床检验中心/北京市临床检验工程技术研究中心,北京 100730
Author(s):
LIU Jia-li; WANG Wei; HE Fa-lin; ZHONG Kun; YUAN Shuai; ZHANG Zhi-xin; DU Yu-xuan;  WANG Zhi-guo
Beijing Hospital,National Center of Gerontology,National Center for Clinical Laboratories/Beijing Engineering Research Center of Laboratory Medicine,Beijing 100730,China
关键词:
降钙素原;  室内质控;  变异系数
分类号:
R446
DOI:
10.3969/j.issn.1671-7414.2018.02.001
文献标志码:
A
摘要:
目的 了解全国血清降钙素原项目室内质量控制变异系数质量水平现状。方法 采用基于Web方式的室间质量评价(EQA)软件系统。收集参加卫生部临床检验中心血清降钙素原项目室间质量评价实验室的室内质量控制数据,包括2017年3月和累积室内质控2个水平(批号1和批号2)在控数据的变异系数(CV)。使用Microsoft Office Excel 2007对数据进行处理分析,依据1/3TEa(室间质量评价限)、1/4TEa计算两个批号的室内质控变异系数的通过率。根据参加EQA的实验室室内质控所使用的仪器进行分组统计,并按两个评价标准计算各组的通过率。根据实验室检测系统是否配套,计算满足两个标准的实验室所占比例。结果 相同评价标准下两个批号的通过率接近,批号2的通过率相对更高。按仪器分组后各组通过率参差不齐。根据实验室检测系统是否配套进行统计分析,使用配套系统较使用非配套系统不精密度符合率更高。结论 应加强室内质量控制,进一步提高检测质量水平。实验室应重视室内质量控制工作,以保证检测结果的可靠性。
Abstract:
Abstract:Objective To investigate the current status ofthe coefficients variations(CVs)of internal quality control(IQC)data forserum procalcitonin in China.Methods Data had been collected by Web-based submission system,the laboratories which enrolled in 2017 serum procalcitonin external quality assessment(EQA)program had attended.The data had included:the CVs of two levels of IQC materials(level 1 and 2)inMarch of 2017 and long-term cumulative in-control data.Microsoft Office Excel2007 was used to analyze and process the data,the acceptable rates of CVswere calculated based on the 1/3TEa and 1/4TEa standards.The instruments whichwas used in laboratory internal quality control system of EQA,were grouped andcounted,the acceptable rates of each group was calculated according to two evaluation standards.According to the laboratory detecting system was matched or not,to calculate the proportion of laboratories,and to adapt to the two standards.Results The acceptable rates of the same standards were close and the acceptable rates of level 2 were relatively higher.After grouping according to the instruments,the acceptable rates of each group were uneven.According to the laboratory detecting system was matched or not,the acceptable rates of the matching system were much more higher.Conclusion To strengthen internal quality control system,and to improve the detection quality level much further.Laboratory should pay more attention to the mission of internal quality control,in order to ensure the reliability of test results.

参考文献/References:

[1] Becker KL,Snider R,Nylen ES,et al.Procalcitonin assay in systemic inflammation,infection,and sepsis:clinical utility and limitations[J].Critical Care Medicine,2008,36(3):941-952.
[2] 李沛然,苑文雯,王 晗,等.两种降钙素原定量检测试剂盒的比较研究[J].检验医学与临床,2015,12(19):2873-2874,2877. Li PR,Yuan WW,Wang H,et al.Comparative study of two kinds of procalcitonin quantitative detection kit[J].Laboratory Medicine and Clinic,2015,12(19):2873-2874,2877.
[3] 张 凤.血清降钙素原与高敏C反应蛋白早期诊断新生儿脓毒血症价值[J].中华实用诊断与治疗杂志,2014,28(1):85-86. Zhang F.Value of serum procalcitonin and high sensitivity C-reactive protein to the diagnosis of early neonatal sepsis[J].Journal of Chinese Practical Diagnosis and Therapy,2014,28(1):85-86.
[4] 徐爱蕾,王 为.降钙素原检测方法学和临床意义的研究进展[J].临床军医杂志,2012,40(1):242-244. Xu AL,Wang W.Progress in the study of methodology and clinical significance on procalcitonin detection[J].Clinical Journal of Medical Officer,2012,40(1):242-244.
[5] 刘振国,王 婷,王顺达,等.重型肝炎并发脓毒症患者血清降钙素原、血乳酸及肉毒素水平的相关研究[J].现代检验医学杂志,2017,32(2):95-97,164. Liu ZG,Wang T,Wang SD,et al.Crelational rea-search of the levelof plasma procalcitonin,blood lactic acid and endotoxin in patients of severepneumonia complicated with sepsis[J].Journal of Modern Laboratory Medicine,2017,32(2):95-97,164.
[6] 张 路,王 薇,何法霖,等.B型钠尿肽和N末端B型钠尿肽原室内质量控制变异系数调查与分析[J].临床检验杂志,2015,33(8):635-637. Zhang L,Wang W,He FL,et al.Analysis of the coefficients of variation for the internal quality control of BNP/NT-pro BNP[J].Chinese Journal of Clinical Laboratory Science,2015,33(8):635-637.
[7] 卫生部临床检中心.卫生部临床检验中心室间质量评价标准[EB/OL].2017,2(4).http://www.clinet.com.cn/plan/?type=list&classid=1384&years=2017&labcenterid=11 National Center for Clinical Laboratoies.National Center for Clinical Laboratoies External Quality Assessment Standards[EB/OL].2017.2.4.http://www.clinet.com.cn/plan/?type=list&classid=1384&years=2017&labcenterid=11
[8] Clinical and Laboratory Standards Institute.Statistical Quality Control for Quantitative Measurement Procedures.principles and definitions; approved guideline-third edition[S].Wayne:PA.CLSI C24-A3,2006.
[9] Westgard JO.Basic QC Practices,3rd edition[M].WI:Westgard QC,Inc,2010.
[10] 叶圆圆,王 薇,何法霖,等.我国新生儿遗传代谢病串联质谱筛查室内质控变异系数分析[J].临床检验杂志,2016,34(12):901-903. Ye YY,Wang W,He FL,et al.Analysis of the coefficients of variation for the internal quality control of newborn inherited metabolic diseases screeningwith tandem mass spectrometry[J].Chinese Journal of Clinical Laboratory Science,2016,34(12):901-903.

相似文献/References:

[1]张培育,邓演超,李全双.自制C肽质控品及其性能评价[J].现代检验医学杂志,2016,31(03):156.[doi:10.3969/j.issn.1671-7414.2016.03.044]
　ZHANG Pei-yu,DENG Yan-chao,LI Quan-shuang.Evaluate Performance of the Self-made Quality Control Products for C Peptide by Mixed Serums[J].Journal of Modern Laboratory Medicine,2016,31(02):156.[doi:10.3969/j.issn.1671-7414.2016.03.044]
[2]张 路,王 薇,何法霖,等.国内临床实验室同型半胱氨酸室内质量控制变异系数调查与分析[J].现代检验医学杂志,2015,30(04):132.[doi:10.3969/j.issn.1671-7414.2015.04.040]
　ZHANG Lu,WANG Wei,HE Fa-lin,et al.Investigation and Analysis of the Coefficient of Variation of Internal Quality Control of Homocysteine[J].Journal of Modern Laboratory Medicine,2015,30(02):132.[doi:10.3969/j.issn.1671-7414.2015.04.040]
[3]周玉宝a,陈芦斌b,刘芳a,等.腹腔镜与ERCP手术后血清CRP和PCT检测比较分析[J].现代检验医学杂志,2015,30(05):4.[doi:10.3969/j.issn.1671-7414.2015.05.002]
　ZHOU Yu-baoa,CHEN Lu-binb,LIU Fanga,et al.Comparative Analysis of Serum CRP and PCT Detection after ERCP and Laparoscopic Operation[J].Journal of Modern Laboratory Medicine,2015,30(02):4.[doi:10.3969/j.issn.1671-7414.2015.05.002]
[4]刘运双.血清降钙素原水平预示革兰阴性菌血症的价值评估[J].现代检验医学杂志,2015,30(02):77.[doi:10.3969/j.issn.1671-7414.2015.02.024]
　LIU Yun-shuang.Values of Procalcitonin Level in Serum for Predicting Gram-negative Bacteremia[J].Journal of Modern Laboratory Medicine,2015,30(02):77.[doi:10.3969/j.issn.1671-7414.2015.02.024]
[5]文 艳,刘爱胜,张 勇,等.ICU危重病患者深部真菌感染血清中降钙素原和（1,3)-β-D葡聚糖联合检测的临床意义[J].现代检验医学杂志,2015,30(02):120.[doi:10.3969/j.issn.1671-7414.2015.02.037]
　WEN Yan,LIU Ai-sheng,ZHANG Yong,et al.Diagnosis Value of Joint Detection of Critical Patients Procalcitonin and(1,3)-beta-D Glucan with Deep Fungus Infection in ICU[J].Journal of Modern Laboratory Medicine,2015,30(02):120.[doi:10.3969/j.issn.1671-7414.2015.02.037]
[6]马志超,黄白丽,阮和球,等.降钙素原联合呼吸道病原体抗体检测在小儿肺炎的诊断价值[J].现代检验医学杂志,2015,30(02):144.[doi:10.3969/j.issn.1671-7414.2015.02.046]
　MA Zhi-chao,HUANG Bai-li,RUAN He-qiu,et al.Diagnosis Value of PCT Combined with Respiratory Pathogen Detection in Pneumonia in Children[J].Journal of Modern Laboratory Medicine,2015,30(02):144.[doi:10.3969/j.issn.1671-7414.2015.02.046]
[7]费阳,王薇,何法霖,等.尿液定量生化检验项目室内质量控制变异系数调查与分析[J].现代检验医学杂志,2016,31(06):154.[doi:10.3969/j.issn.1671-7414.2016.06.046]
　FEI Yang,WANG Wei,HE Fa-lin,et al.Investigation and Analysis of the Coefficient of Variation of Internal Quality Control of Quantitative Urine Chemistry[J].Journal of Modern Laboratory Medicine,2016,31(02):154.[doi:10.3969/j.issn.1671-7414.2016.06.046]
[8]尹良琼,余艾霞.降钙素原、胱抑素C联合检测对脓毒症患儿28天死亡率的预测价值研究[J].现代检验医学杂志,2017,32(02):153.[doi:10.3969/j.issn.1671-7414.2017.02.043]
　YIN Liang-qiong,Y Ai-xia.Predictive Value of the Combined Detection of Procalcitonin and Cystatin C in Children with Sepsis 28 Days Mortality[J].Journal of Modern Laboratory Medicine,2017,32(02):153.[doi:10.3969/j.issn.1671-7414.2017.02.043]
[9]严海忠,王伟佳,慕月晶,等.血液及尿液中降钙素原(PCT检测在泌尿系统感染定位中的诊断价值[J].现代检验医学杂志,2017,32(04):116.[doi:10.3969/j.issn.1671-7414.2017.04.033]
　YAN Hai-zhong,WANG Wei-jia,MU Yue-jing,et al.Diagnostic Value of Detecting the Serum and Urine Procalcitonin(PCT)for the Urinary System Infection[J].Journal of Modern Laboratory Medicine,2017,32(02):116.[doi:10.3969/j.issn.1671-7414.2017.04.033]
[10]王臣玉,杨丽萍,陈 磊,等.两种降钙素原检测系统比较实验研究[J].现代检验医学杂志,2017,32(04):143.[doi:10.3969/j.issn.1671-7414.2017.04.041]
　WANG Chen-yu,YANG Li-ping,CHEN Lei,et al.Methodology Comparison Study on Two Analysis Systems of Procalcitonin[J].Journal of Modern Laboratory Medicine,2017,32(02):143.[doi:10.3969/j.issn.1671-7414.2017.04.041]

备注/Memo

备注/Memo:
作者简介:刘佳丽(1990-),女,本科,检验技师,研究方向:实验室质量管理,E-mail:1253480821@qq.com。 通讯作者:王治国(1964-),硕士,研究员,临床实验室质量管理,E-mail:zgwang@nccl.org.cn。
更新日期/Last Update: 2018-04-16