[1]王李秦,魏绪仓.Galectin-4与肿瘤相关性的研究进展[J].现代检验医学杂志,2019,34(01):161-164.[doi:10.3969/j.issn.1671-7414.2019.01.042]
　WANG Li-qin,WEI Xu-cang.Research of Galectin-4 in Tumor[J].Journal of Modern Laboratory Medicine,2019,34(01):161-164.[doi:10.3969/j.issn.1671-7414.2019.01.042]
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Galectin-4与肿瘤相关性的研究进展()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第34卷
期数:
2019年01期
页码:
161-164
栏目:
综述
出版日期:
2019-02-28

文章信息/Info

Title:
Research of Galectin-4 in Tumor
文章编号:
1671-7414(2019) 01-161-04
作者:
王李秦1; 2; 魏绪仓2
(1.西安医学院，西安 710068；2.陕西省人民医院血液病研究室，西安710068)
Author(s):
WANG Li-qin1; 2; WEI Xu-cang2
(1.X i’an Medical University，Xi’an 710068，China；2.Department of Hematology Laboratory，Shaanxi Provincial People’s Hospital，Xi’an 71 0 068，China)
关键词:
半乳凝集素-4; 肿瘤
分类号:
R730.43
DOI:
10.3969/j.issn.1671-7414.2019.01.042
文献标志码:
A
摘要:
Galectin-4是半乳凝集素(galectins)亚家族成员，广泛分 布于各种动植物组织中，并参与各种如细胞增殖、凋亡、黏附、信号转导等功能。近几年， Galectin-4在生理及病理过程中所起的作用正日益受到人们的重视。目前发现Galectin-4 的低表达与结肠癌、肝癌、肺癌、尿路上皮癌等多种肿瘤的预后不良相关，有望成为判断肿 瘤预后的可靠检测指标。
Abstract:
Galectin-4 is a member of Galectins subfamily， widely distributed in various animal and plant tissues，and is involved in vario us functions such as cell proliferation，apoptosis，adhesion and signal transduc tion．In recent years，galectin-4 plays an increasingly important role in physi ological and pathological processes．Although there is no unified conclusion on the expression of galectin-4 in the tissues of various types of tumors，it has been found that the low expression of galectin-4 is related to the poor prognos is of colon cancer，liver cancer，lung cancer，urinary tract epithelial cancer a nd other tumors，making it possible to become a reliable indicator for the progn osis of tumors．

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备注/Memo

备注/Memo:
基金项目：西安 市科技计划201805095YX3SF29(9)。
作者简介：王李秦(1992-)，女，在读硕士研究生，主要研究方向 ：分子检验，E-mail：xpwlqd@163.com。
通讯作者：魏绪仓，男，主任技师，研究员，主要研究方向：血 液病形态诊断，E-mail：weixucang62@sina.com。
更新日期/Last Update: 2019-02-28