[1]史剑飞,卢北玲,李　俏,等.西安地区健康儿童血清缺血修饰清蛋白参考区间的建立[J].现代检验医学杂志,2019,34(06):118-119.[doi:10.3969 ／ j.issn.1671-7414.2019.06.029]
　SHI Jian-fei,LU Bei-ling,LI Qiao,et al.Establishment of Reference Interval for Serum Ischemic Modified Albumin of Healthy Children in Xi’an Area[J].Journal of Modern Laboratory Medicine,2019,34(06):118-119.[doi:10.3969 ／ j.issn.1671-7414.2019.06.029]
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西安地区健康儿童血清缺血修饰清蛋白参考区间的建立 ()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第34卷
期数:
2019年06期
页码:
118-119
栏目:
研究简报·实验技术
出版日期:
2019-12-30

文章信息/Info

Title:
Establishment of Reference Interval for Serum Ischemic Modified Albumin of Healthy Children in Xi’an Area
文章编号:
1671-7414（2019）06-118-03
作者:
史剑飞1; 卢北玲2; 李　俏1; 毛　瑞1; 曹三成1; 宁远征1
（1. 西安市儿童医院检验科，西安 710003；2. 西安市中医医院检验科，西安 710021）
Author(s):
SHI Jian-fei1; LU Bei-ling2; LI Qiao1; MAO Rui1; CAO San-cheng1; NING Yuan-zheng1
（1.Department of Clinical Laboratory，Xi’an Children’s Hospital,Xi’an 710003,China；2.Department of Clinical Laboratory,Xi’an Hospital of Traditional Chinese Medicine,Xi’an 710021,China）
关键词:
儿童; 缺血修饰清蛋白; 参考区间; 氧化应激
分类号:
R446.112
DOI:
10.3969 ／ j.issn.1671-7414.2019.06.029
文献标志码:
A
摘要:
目的　初步建立西安地区健康儿童血清缺血修饰清蛋白(ischemia- modified albumin，IMA) 参考区间。方法　收集 西安市儿童医院保健科2019 年7~8 月260 例健康体检儿童，其中按性别分为男性组140 例，女性组120 例；按年龄分为 ≤ 1 岁组41 例、1~3 岁组56 例和≥ 3 岁组163 例，采用清蛋白- 钴结合法检测血清IMA 并进行统计学分析。结果　西安 地区健康儿童血清IMA 呈偏态分布，男性组、女性组、≤ 1 岁组、1~3 岁组和≥ 3 岁组的IMA 水平分别为70.47±2.64， 69.61±3.14，69.71±3.27，70.66±2.77 和69.97±2.87 U/ml。不同性别间儿童IMA 表达差异有统计学意义（U=6 954, P <0.05），不同年龄组间IMA 表达差异无统计学意义（H =1.813，P >0.05）。西安地区健康儿童血清IMA 参考区间为：男 性0~74.00 U/ml，女性0~75.76 U/ml。结论　初步建立西安地区健康儿童血清IMA 参考区间，为儿童临床疾病氧化应激损 伤的诊断及评估提供参考依据。
Abstract:
Objective　To establish a reference interval for ischemic-modified albumin (IMA) in healthy children in Xi’an area. Methods　A total of 260 healthy children from July to August 2019 who were examined in the Department of Child Health Care in the Xi’an Children’s Hospital were collected.There were 140 males and 120 females by sex.They were divided into ≤ 1 years old group 41 cases，1~3 years old group 56 cases and ≥ 3 years old group 163 cases. Serum IMA levels were measured by albumin-cobalt binding assay and analyzed by statistical methods. Results　The serum IMA expression level of healthy children in Xi’an Area was skewed.The IMA levels of the male group，the female group，≤ 1 years old group，1~3 years old group and ≥ 3 years old group were 70.47±2.64,69.61±3.14,69.71±3.27,70.66±2.77 和69.97±2.87 U/ml,respectively.The difference of serum IMA levels between different genders was statistically significant (U=6 954, P <0.05).There was no significant difference in serum IMA levels between different age groups (H=1.813, P >0.05).The reference range of serum IMA level for healthy children in Xi’an Area was 0~74.00 U/ml, for male, and 0~75.76 U/ml for female. Conclusion　The serum IMA reference interval of healthy children in Xi’an Area was preliminarily established,which will provides a reference for the clinical diagnosis of childhood diseases oxidative stress injury and evaluation.

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备注/Memo

备注/Memo:
基金项目：西安市儿童医院院级项目（2018E12）。 作者简介：史剑飞（1990-），男，硕士，检验师，研究方向：RV 胃肠炎的生化相关性研究，E-mail：981230877@qq.com。 通讯作者：宁远征（1982-），女，本科，主管检验师，研究方向：RV 胃肠炎的生化相关性研究，E-mail：861902427@qq.com 收稿日期：2019-08-23　
更新日期/Last Update: 2019-12-25