参考文献/References:
[1] 颜丽，魏莲花，齐发梅，等．血清TSGF,AFP,CEA和FER 联合检测在肝脏恶性肿瘤诊断中的应用价值[J]．现代检验医学杂志, 2018, 33（5）: 24-26，141.YAN Li, WEI Lianhua, QI Famei, et al. Significance ofcombined detection of TSGF, AFP, CEA and FER in thediagnosis of hepatic malignancy[J]. Journal of ModernLaboratory Medicine, 2018,33(5):24-26,141.
[2] HU Zhangyong ，ZHOU Zhipeng ，XIONG Guolian,et al. Cyclin D1 G870A polymorphism and the risk ofhepatocellular carcinoma in a Chinese population[J].Tumour Biology, 2014, 35(6): 5607-5612.
[3] NEWELL P, TOFFANIN S, VILLANUEVA A, et al.Ras pathway activation in hepatocellular carcinomaand anti-tumoral effect of combined sorafenib andrapamycin in vivo[J]. Journal of Hepatology, 2009,51(4): 725-733.
[4] 吴良银，李文丽，刘俊．肝细胞癌患者生存预后相关长链非编码RNA(LncRNA) 的生物信息学分析[J].现代检验医学杂志, 2019, 34（4）:18-21．WU Liangyin, LI Wenli, LIU Jun. Bioinformaticsanalysis of long-chain non-coding RNA related tosurvival and prognosis in patients with hepatocellularcarcinoma[J]. Journal of Modern LaboratoryMedicine,2019,34(4):18-21.
[5] EDGAR R, DOMRACHEV M, LASH A E. Geneexpression omnibus :NCBI gene expression andhybridization array data repository[J]. Nucleic AcidsResearch, 2002, 30(1): 207-210.
[6] CALDERARO J, MEUNIER L, NGUYEN C T, etal. ESM1 as a marker of Macrotrabecular-Massivehepatocellular carcinoma[J]. Clinical Cancer Research,2019, 25(19): 5859-5865.
[7] SUNG Changmu, LIN Yufei, CHEN Kuanfu, et al.Predicting clinical outcomes of cirrhosis patients withhepatic encephalopathy from the fecal microbiome[J].Cell Mol Gastroenterol Hepatol, 2019, 8(2): 301-318，e2.
[8] Shimada S , Mogushi K, Akiyama Y, e t a l .Comprehensive molecular and immunologicalcharacterization of hepatocellular carcinoma[J].EBioMedicine,2019,40:457-470.
[9] HUANG Dawei, SHERMAN B T, TAN Qina, etal. The DAVID gene functional classification tool:a novel biological module-centric algorithm tofunctionally analyze large gene lists[J]. GenomeBiol,2007,8(9):R183.
[10] FRANCES C H I N I A，SZKLARCZYK D，FRANKILD S, et al. STRING v9.1: protein-proteininteraction networks, with increased coverage andintegration [J]. Nucleic Acids Res,2013,41(Databaseissue):D808-D815.
[11] SMOOT M E, ONO K, RUSCHEINSKI J, et al.Cytoscape 2.8:new features for data integration andnetwork visualization[J]. Bioinformatics, 2011, 27(3):431-432.
[12] HAEUSSLER M, ZWEIG A S, TYNER C, et al. TheUCSC genome browser database:2019 update[J].Nucleic Acids Research, 2019, 47(D1): D853-D858.
[13] EL-SERAG H B. Rudolph K L. Hepatocellularc a r c i n o m a : e p i d e m i o l o g y a n d m o l e c u l a rcarcinogenesis[J]. Gastroenterology, 2007, 132(7):2557-2576.
[14] WANG Yongfeng, CHENG Jin, XU Chunhui, et al.Quantitative methylation analysis reveals gender andage differences in p16INK4a hypermethylation inhepatitis B virus-related hepatocellular carcinoma [J].Liver International, 2012, 32(3): 420-428.
[15] CHOI Y L, PARK S H, JANG J J, et al. Expressionof the G1-S modulators in hepatitis B virus-relatedhepatocellular carcinoma and dysplastic nodule:association of cyclin D1 and p53 proteins with theprogression of hepatocellular carcinoma. [J]. Journal ofKorean Medical Science, 2001, 16(4): 424-432.
[16] SIA D, VILLANUEVA A, FRIEDMAN S L, et al. Livercancer cell of origin, molecular class,and effects onpatient prognosis. [J]. Gastroenterology, 2017, 152(4):745-761.
[17] DAULAT A M, FINETTI P, REVINSKI D, et al. ECT2associated to PRICKLE1 are poor-prognosis markersin triple-negative breast cancer[J]. British Journal ofCancer, 2019, 120(9): 931-940.
[18] LU Mingqin, HUANG Xiaoying, CHEN Yongping, etal. Aberrant KIF20A expression might independentlypredict poor overall survival and recurrence‐freesurvival of hepatocellular carcinoma [J]. IUBMB Life,2018, 70(4): 328-335.
[19] YANG Qiuxia, ZHONG Shan, HE Lin, et al. PBKoverexpression promotes metastasis of hepatocellularcarcinoma via activating ETV4-uPAR signalingpathway [J]. Cancer Lett,2019,452:90-102.
[20] LIN Yinghung, KE Chihchun,WANG Yayun, et al.RAB10 interacts with the male germ cell-specificGTPase-activating protein during mammalianspermiogenesis[J]. International Journal of MolecularSciences,2017,18(1):97.
[21] YANG Xiaomei, CAO Xiaoyan, HE Ping , et al.Overexpression of rac GTPase activating protein1 contributes to proliferation of cancer cells byreducing hippo signaling to promote cytokinesis[J].Gastroenterology,2018,155(4): 1233-1249,e22.
[22] YANG Xiaoyu ,WU Bin, MA Senl in , et al .Decreased expression of ZWINT is associatedwith poor prognosis in patients with HCC aftersurgery[J]. Technology in Cancer Research & Treatment,2018,17:1533033818794190.
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