[1]许　涛a,杨　磊b,高玉芳a,等.中国地区新型冠状病毒感染者的密切接触人群SARS-CoV-2核酸阳性率的meta分析[J].现代检验医学杂志,2021,36(04):122-128.[doi:10.3969/j.issn.1671-7414.2021.04.026]
　XU Taoa,YANG Leib,GAO Yu-fanga,et al.SARS-CoV-2 Nucleic Acid Positive Rate among Close Contacts of thePatients Infected with Novel Coronavirus in China:A Meta-Analysis[J].Journal of Modern Laboratory Medicine,2021,36(04):122-128.[doi:10.3969/j.issn.1671-7414.2021.04.026]
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中国地区新型冠状病毒感染者的密切接触人群SARS-CoV-2核酸阳性率的meta分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第36卷
期数:
2021年04期
页码:
122-128
栏目:
新型冠状病毒肺炎检验专题
出版日期:
2021-07-31

文章信息/Info

Title:
SARS-CoV-2 Nucleic Acid Positive Rate among Close Contacts of thePatients Infected with Novel Coronavirus in China:A Meta-Analysis
文章编号:
1671-7414（2021）04-122-07
作者:
许　涛a; 杨　磊b; 高玉芳a; 张建平a
（咸阳市中心医院 a. 检验科；b. 生殖医学科，陕西咸阳 712000）
Author(s):
XU Taoa;  YANG Leib;  GAO Yu-fanga;  ZHANG Jian-pinga
（a. Department of Clinical Laboratory; b. Department of Reproductive Medicine, Xianyang Central Hospital,Shaanxi Xianyang 712000, China）
关键词:
新型冠状病毒病; 密切接触者; 严重急性呼吸综合征冠状病毒2; 核酸; 阳性率
分类号:
R373.1；R446
DOI:
10.3969/j.issn.1671-7414.2021.04.026
文献标志码:
A
摘要:
目的　了解中国地区新型冠状病毒感染者的密切接触人群严重急性呼吸综合征冠状病毒（SARS-CoV-2）核酸阳性率的现状。方法　检索PubMed，EMbase，中国期刊全文数据总库（CNKI）、万方科技期刊全文数据库、维普中文科技期刊全文数据库（VIP）中有关中国地区新型冠状病毒感染者的密切接触人群SARS-CoV-2 核酸检测相关文献，检索时间为2019 年12 月~2020 年12 月24 日。参照修改后的美国卫生保健研究与质量机构（AHRQ）声明评价文献质量。采用StataSE15.0 软件进行meta 分析，利用Freeman-Tukey 双反正弦转换法计算合并的阳性率，根据性别、年龄、感染人员关系、感染方式及接触频率进行亚组分析，并进行敏感性分析及Egger 法检验发表偏倚。结果　共纳入11 篇文献，总样本量为24 906 例，新型冠状病毒感染者的密切接触人群SARS-CoV-2 核酸阳性率为5.42%（95%CI：3.57%~7.64%），亚组分析显示，男性阳性率为4.35%，女性阳性率为6.36%；0~9 岁组阳性率为5.88%，10~59 岁组为4.76%，≥ 60 岁组为8.73%；家庭成员组阳性率为13.42%，其它为2.09%；共同生活人员阳性率为11.44%，聚餐为9.90%，其它感染方式组为1.95%；偶尔接触者、一般接触者、经常接触者阳性率分别为1.32%，6.12% 和9.60%，各亚组间差异均有统计学意义（χ2=37.89~809.90，均P <0.05）。敏感度分析提示结果稳定，Egger 法检验发表偏倚为差异无统计学意义（t=0.93，P =0.376）。结论　中国地区新型冠状病毒感染者的密切接触人群SARS-CoV-2 核酸具有一定的阳性率。

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[1]许 涛a,高玉芳a,刘振社a,等.中国地区COVID-19 康复者SARS-CoV-2 特异性抗体IgG 阳性率动态变化的meta 分析[J].现代检验医学杂志,2022,37(06):134.[doi:10.3969/j.issn.1671-7414.2022.06.025]
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备注/Memo

备注/Memo:
作者简介： 许涛（1987-），男，硕士，主管检验师，研究方向：分子生物实验室病毒核酸诊断及其流行病学调查，E-mail：dazhuxt126@126.com。
通讯作者：杨磊（1991-），女，硕士，主管检验师，研究方向：临床检验诊断学，E-mail：shangcl21@163.com。
更新日期/Last Update: 1900-01-01