[1]朱传新,周玉平,何 艳,等.92 例新冠肺炎病毒感染患者早期外周血白细胞形态分析[J].现代检验医学杂志,2020,35(03):94-96.[doi:10.3969/j.issn.1671-7414.2020.03.024]
 ZHU Chuan-xin,ZHOU Yu-ping,HE Yan,et al.Morphological Analysis of Early Peripheral Blood Leukocytes in 92 Patients with New Coronary Pneumonia[J].Journal of Modern Laboratory Medicine,2020,35(03):94-96.[doi:10.3969/j.issn.1671-7414.2020.03.024]
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92 例新冠肺炎病毒感染患者早期外周血白细胞形态分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第35卷
期数:
2020年03期
页码:
94-96
栏目:
新型冠状病毒肺炎检验专题
出版日期:
2020-07-20

文章信息/Info

Title:
Morphological Analysis of Early Peripheral Blood Leukocytes in 92 Patients with New Coronary Pneumonia
文章编号:
1671-7414(2020)03-094-04
作者:
朱传新周玉平何 艳周 琴
(咸宁市第一人民医院,湖北咸宁437000)
Author(s):
ZHU Chuan-xin ZHOU Yu-ping HE YanZHOU Qin
(the First People’s Hospital of Xianning City, Hube Xianning 437000,China)
关键词:
新型冠状病毒肺炎白细胞分类白细胞形态
分类号:
R373.1 R446.113
DOI:
10.3969/j.issn.1671-7414.2020.03.024
摘要:
目的  探讨新型冠状病毒肺炎(COVID-19)患者早期外周血白细胞分类和形态特征。方法 对2020 年1 月 26 日~ 2 月28 日咸宁市第一人民医院收治的92 例COVID-19 患者及同期收治的259 例其他病毒导致的病毒性肺炎 (非COVID-19)患者一般情况比较、血白细胞分类和形态分析。结果 与非COVID-19 组相比,COVID-19 组男性比 例偏高,年龄偏大,胸部CT 病毒性肺炎表现比例偏高,差异均有统计学意义(χ2 或t 为7.027~21.551,均P<0.05)。 COVID-19 组中性粒细胞比率(NEU%) 为66.00%(62.00% 和69.50%), 中性粒细胞杆核比率(Nst%)31.00% (20.00% 和39.00%);嗜酸性粒细胞比率(EOS%)0%(0% 和1.00%);淋巴细胞比率(LYM%)22.50%(15.00% 和27.00%);异形淋巴细胞比率(异淋%)0%(0% 和1.00%);中性粒细胞杆核与分叶核之比(Nst/Nsg)2.26(0.44 和6.06). 与非COVID-19 组相比,COVID-19 组异淋%,NEU%,Nst% 和Nst/ Nsg 较高,EOS% 和LYM% 较低,差 异均有统计学意义(t 为4.037~61.209,均P<0.05)。COVID-19 组白细胞间接计数较低,NEU,EOS,LYM,异淋和 MONO 形态异形多样且明显。结论 COVID-19 组外周血白细胞分类和形态变化明显,在早期鉴别诊断价值较高,值 得推广。
Abstract:
Objective To investigate the classification and morphological characteristics of early peripheral blood leukocytes in patients with new coronavirus pneumonia (COVID-19). Methods The blood of 92 patients with COVID-19 treated by the First People’s Hospital of Xianning City from January 26 to February 28, 2020 and 259 patients with viral pneumonia (non-COVID-19) caused by other viruses during the same period,WBCs were classified and morphologically analyzed. Results 92 cases of covid-19 were mostly middle-aged and old men, and the manifestations of chest CT virus pneumonia were earlier, the differences were statistically significant(χ2/t was 7.027~21.551, all P<0.05). The neutrophil ratio (NEU%) was 66.00% (62.00% and 69.50%), the rod nucleus of neutrophils ratio (NST%) was 31.00% (20.00% and 39.00%), the eosinophil ratio (EOS%) was 0% (0% and 1.00%), the lymphocyte ratio (LYM%) was 22.50% (15.00% and 27.00%), the heteromorphic lymphocyte ratio (isolymph%) was 0% (0% and 1.00%), and the neutrophil stem cell ratio (NST / NSG) was 2.26(0.44 and 6.06). Compared with the noncovid- 19 group, the% of NST%, NST%, NST / NSG and allolymph in the covid-19 group was higher, while the % of lym and EOS in the covid-19 group was lower (t=4.037~61.209, all P < 0.05). In patients with covid-19, the morphology of leukocyte changed obviously, the cell body of lymphocyte was small, the nucleus was easy to see notch, and the majority of them were petal nuclear lymph and fissure nuclear lymph. Conclusion In the covid-19 group, the classification and morphological changes of peripheral blood leukocytes were obvious, which had high value in early differential diagnosis and was worth popularizing.

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备注/Memo

备注/Memo:
收稿日期:2020-03-18 修回日期:2020-04-1作者简介:朱传新(1966-),男,大学本科,副主任技师,主要研究方向为免疫和血液细胞,E-mail:248978208@qq.com
更新日期/Last Update: 2020-07-20