[1]张 宁,陆学东,吴正林.飞行时间质谱技术在糖尿病肾病患者尿蛋白成分分析中的研究进展[J].现代检验医学杂志,2016,31(05):160-164.[doi:10.3969/j.issn.1671-7414.2016.05.048]
　ZHANG Ning,LU Xue-dong,WU Zheng-lin.Research Advancement of TOF-MS for Analysising Protein Components in Patients with Diabetic Nephropathy Urine[J].Journal of Modern Laboratory Medicine,2016,31(05):160-164.[doi:10.3969/j.issn.1671-7414.2016.05.048]
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飞行时间质谱技术在糖尿病肾病患者尿蛋白成分分析中的研究进展()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第31卷
期数:
2016年05期
页码:
160-164
栏目:
综述
出版日期:
2016-10-21

文章信息/Info

Title:
Research Advancement of TOF-MS for Analysising Protein Components in Patients with Diabetic Nephropathy Urine
文章编号:
1671-7414(2016)05-160-05
作者:
张 宁1; 陆学东2; 吴正林2
1.陕西中医药大学,陕西咸阳 712046;
2.深圳市第四人民医院,广东深圳 518033
Author(s):
ZHANG Ning1; LU Xue-dong2; WU Zheng-lin2
1.Shaanxi University of Traditional Chinese Medicine,Shaanxi Xianyang 712046,China;
2.the Fourth People's Hospital of Shenzhen,Guangdong Shenzhen 518033,China
关键词:
质谱;  糖尿病肾病;  生物标记物
分类号:
R587.2; Q503
DOI:
10.3969/j.issn.1671-7414.2016.05.048
摘要:
飞行时间质谱技术(time of flight mass spectrometry,TOF-MS)由于其快速易操作等优点,已经越来越广泛的应用于临床和科研。糖尿病肾病是糖尿病最常见的并发症,但临床现有的检测方法在一定程度上具有一定的滞后性,飞行时间质谱等蛋白组学相关技术的应用和发展,为糖尿病肾病的早期诊断及预后等方面提供了新的方法和思路。该文就近几年国内外应用TOF-MS在糖尿病肾病方面取得的最新研究成果进行综述。
Abstract:
TOF-MS has been more and more widely used in clinical and scientific research due to its advantages such as fast and easily operated.Diabetic nephropathy is the most common complications of diabetes.But clinical existing detection methods to some extent have some hysteresis.The applications and developments of TOF-MS coupled with other proteomics technologies provided new ideas and methods for early diagnosis and prognosis of diabetic nephropathy.In this paper,the latest research results in nearest years about the application of TOF-MS to diabetic nephropathy will be reviewed.

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备注/Memo

备注/Memo:

作者简介:张 宁(1990-),女,在读硕士研究生,初级检验技师,研究方向:尿蛋白组学,Tel:13189735292,E-mail:348068953@qq.com。
通讯作者:陆学东。
更新日期/Last Update: 2016-10-30