[1]潘永圣,蒲　丹,汪佳婕,等.昆明地区儿童血清 25羟基维生素 D水平检测及维生素 D营养状态分析[J].现代检验医学杂志,2021,36(01):116-119.[doi:10.3969/j.issn.1671-7414.2021.01.029]
　PAN Yong-sheng,PU Dan,WANG Jia-jie,et al.Detection of Sorum 25-Hydroxyvitamin D Level and Analysis of Vitamin D Status in Children in Kunming[J].Journal of Modern Laboratory Medicine,2021,36(01):116-119.[doi:10.3969/j.issn.1671-7414.2021.01.029]
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昆明地区儿童血清 25羟基维生素 D水平检测及维生素 D营养状态分析()
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《现代检验医学杂志》[ISSN:/CN:]

卷:
第36卷
期数:
2021年01期
页码:
116-119
栏目:
检验与临床
出版日期:
2021-02-05

文章信息/Info

Title:
Detection of Sorum 25-Hydroxyvitamin D Level and Analysis of Vitamin D Status in Children in Kunming
文章编号:
1671-7414（2021）01-116-04
作者:
潘永圣; 蒲　丹; 汪佳婕; 等
(昆明市第一人民医院检验科，昆明 650011)
Author(s):
PAN Yong-sheng;  PU Dan;  WANG Jia-jie;  et al
(Department of Laboratory Medicine, the First People’s Hospital of Kunming, Kunming 650011, China)
关键词:
儿童; 血清 25羟基维生素 D; 维生素 D
分类号:
R591.44；R446.112
DOI:
10.3969/j.issn.1671-7414.2021.01.029
文献标志码:
A
摘要:
目的　了解昆明地区儿童血清 25羟基维生素 D [25（OH）D]水平及维生素 D营养状态，为儿童合理补充维生素 D提供科学依据。方法　选取昆明市第一人民医院 2016年 11月 ~2019年 10月体检儿童 0～ 14岁 600例为研究对象，采用液相色谱串联质谱（ LC-MS/MS）法检测血清 25（OH）D水平，分析不同性别、年龄及季节儿童血清 25（OH）D水平及营养状态。结果　600例 0～ 14岁儿童血清 25（OH）D水平为 27.44±8.82 ng/ml。血清 25（OH）D缺乏率为 19.33%（116/600），不足率为 47.67%（286/600），充足率为 33.00%（198/600）。女童的缺乏率（ 24.83%）高于男童（ 14.33%），儿童血清 25（OH）D的缺乏、不足和充足率在不同性别间差异有统计学意义（ χ2=11.784，P<0.01）。6～ 14岁儿童血清 25（OH）D缺乏率高于 0～ 1岁、1～ 3岁和３～６岁儿童（ 46.81% vs 5.88%，5.86%和 19.53%），血清 25（OH）D的缺乏、不足和充足率在不同年龄段上差异有统计学意义（ χ2=188.515，P<0.01）。夏、冬季的儿童血清 25（OH）D缺乏率高于春、秋季（ 22.00%，27.50% vs 12.80%，11.43%），不同季节血清 25（OH）D的缺乏、不足和充足率差异有统计学意义（ χ2=14.492，P<0.05）。结论　昆明地区 0～ 14岁儿童血清 25（OH）D营养状况欠佳，应加强维生素 D健康宣传工作，提高儿童血清 25（OH）D的监测，特别关注 3～ 14岁阶段儿童维生素 D的补充。

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备注/Memo

备注/Memo:
作者简介：潘永圣（1988-），男，硕士，初级技师，研究方向：临床生化及分子生物学检验， E-mail: panysh88@126.com。
通讯作者：尹利民，副主任技师，E-mail：ylmbj@163.com。
更新日期/Last Update: 2021-02-05